Crisaborole intermediate

 化学構造式
1187188-60-8
CAS番号.
1187188-60-8
化学名:
别名:
英語名:
Crisaborole intermediate
英語别名:
Crisaborole Impurity 28;Crisaborole Impurity 37;Crisaborole Impurity 59;5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol;5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol;Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
CBNumber:
CB68131269
化学式:
C14H13BO4
分子量:
256.06
MOL File:
1187188-60-8.mol

Crisaborole intermediate 物理性質

沸点 :
432.1±55.0 °C(Predicted)
比重(密度) :
1.33±0.1 g/cm3(Predicted)
酸解離定数(Pka):
7.05±0.20(Predicted)

安全性情報

Crisaborole intermediate 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Crisaborole intermediate 化学特性,用途語,生産方法

使用

5-(4-(Hydroxyl Methyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol is an impurity for Crisaborole(H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.

Crisaborole intermediate 上流と下流の製品情報

原材料

準備製品


Crisaborole intermediate 生産企業

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  • 1187188-60-8
  • 5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
  • 5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol
  • Crisaborole Impurity 59
  • Crisaborole Impurity 37
  • Crisaborole Impurity 28
  • Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
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