塩酸トンジルアミン 化学特性,用途語,生産方法
効能
抗アレルギー薬, H1受容体拮抗薬
化学的特性
White, crystalline powder; faint odor. Very soluble in water; freely soluble
in alcohol and chloroform; practically insoluble in
ether and benzene; pH 5.0–6.0 (2% solution).
使用
Medicine (antihistamine).
一般的な説明
Thonzylamine hydrochloride,2-[[2-(dimethylamino)-ethyl](p-methoxybenzyl)amino]pyrimidine hydrochloride, is a white crystallinepowder soluble in water (1:1), in alcohol (1:6), and in chloroform(1:4). A 2% aqueous solution has a pH of 5.5. It is similar in activity to tripelennamine but is claimed to be lesstoxic. The usual dose is 50 mg taken up to 4 times daily. Itis available in certain combination products.
空気と水の反応
Water soluble.
反応プロフィール
thonzylamine hydrochloride behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
健康ハザード
SYMPTOMS: Symptoms of exposure to thonzylamine hydrochloride may include drowsiness, lethargy, fatigue, hypnosis, coma, vertigo, ataxia, tinnitus, blurred vision, tremors, anxiety, insomnia, excitement, hallucinations, delirium, convulsions, dry mouth, anorexia, nausea, vomiting, abdominal distress, constipation, diarrhea, central nervous system depression, gastrointestinal reactions, respiratory arrest and circulatory collapse.
火災危険
Flash point data for thonzylamine hydrochloride are not available. thonzylamine hydrochloride is probably combustible.
塩酸トンジルアミン 上流と下流の製品情報
原材料
準備製品