N-プロパノイル-4-(3-フェニル-5-メチルイソオキサゾール-4-イル)ベンゼンスルホンアミド 化学特性,用途語,生産方法
使用
3-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl Chloride is an Impurity of Parecoxib Sodium (P193275), an anti-inflammatory, analgesic.
臨床応用
Parecoxib is a pro-drug of valdecoxib administered IM or IV for perioperative analgesic and
anti-inflammatory use. As a pro-drug, it undergoes rapid in vivo hydrolysis to valdecoxib.Parecoxib at greater than 20 mg has analgesic activity superior to that of placebo and similar to
that of parenteral 30 or 60 mg of ketorolac in patients with postoperative dental pain. A significant adverse effect is
drug hypersensitivity. Parecoxib is currently marketed worldwide but has not been approved for use in the United
States.
N-プロパノイル-4-(3-フェニル-5-メチルイソオキサゾール-4-イル)ベンゼンスルホンアミド 上流と下流の製品情報
原材料
準備製品