(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE

193146-53-1

CAS番号.: 193146-53-1

化学名:

别名:

英語名:: (3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE

英語别名:: (3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE;12,16-Heptadecadien-5-one, 3,7,15-tris[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-4-thiazolyl)-, (3S,6R,7S,8S,12Z,15S,16E)-

CBNumber:: CB6980421

化学式:: C45H87NO5SSi3

分子量:: 838.5

MOL File:: Mol file

物理性質

安全性情報

用途語

生産企業 9

(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE 物理性質

溶解性:: アセトン、ジクロロメタン、エタノール、酢酸エチル、メタノール

外見 :: 油

色:: 無色

安全性情報

(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE 化学特性,用途語,生産方法

化学的特性

Colourless Oil

使用

An intermediate in the synthesis of Epothilones. Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel- resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arr ests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.

(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE 上流と下流の製品情報

原材料

(3S,6R,7S,8S,12Z,15S,16E)-1,3,7,15-Tetrakis-{[tert-butyl(dimethyl)silyl]oxy}-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)heptadeca-12,16-dien-5-one (5S)-5,7-ビス-{[TERT-ブチルジメチルシリル)オキシ]}-4,4-ジメチルヘプタン-3-オン

準備製品

(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)-5-OXO-HEPTADECA-12,16-DIENOIC ACID

(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE 生産企業

Global( 9)Suppliers

名前	電話番号	電子メール	国籍	製品カタログ	優位度
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58

193146-53-1
(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-1-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECA-12,16-DIEN-5-ONE
12,16-Heptadecadien-5-one, 3,7,15-tris[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-4-thiazolyl)-, (3S,6R,7S,8S,12Z,15S,16E)-