1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン
1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン 物理性質
- 融点 :
- 118-120 °C(Solv: ethyl acetate (141-78-6))
- 比重(密度) :
- 1.161±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- Sealed in dry,Room Temperature
- 溶解性:
- DMSO：20mg/mL以上
- 外見 :
- 粉
- 酸解離定数(Pka):
- 12.29±0.30(Predicted)
- 色:
- 結晶性
- 安定性：:
- DMSO溶液またはエタノール溶液で-20°Cで最大3か月保存できます。
1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン 価格
もっと(17)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS065492 |
1-エチル-1,3-ジヒドロ-2H-ベンズイミダゾール-2-オン
1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one |
10045-45-1 |
1g |
￥76800 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBST-9888 |
1-Ethylbenzimidazolinone |
10045-45-1 |
1g |
￥12500 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS065492 |
1-エチル-1,3-ジヒドロ-2H-ベンズイミダゾール-2-オン
1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one |
10045-45-1 |
5g |
￥255300 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBST-9888 |
1-Ethylbenzimidazolinone |
10045-45-1 |
5g |
￥42500 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBST-9888 |
1-Ethylbenzimidazolinone |
10045-45-1 |
100g |
￥600000 |
2024-03-01 |
購入 |
1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン 化学特性,用途語,生産方法
外観
白色～うすい黄色、結晶性粉末～粉末
説明
1-EBIO is an activator of Ca2+-sensitive K+ channels (EC50 = 490 μM in T84 human carcinoma cells).This action is sensitive to the neurotoxin charybdotoxin (Ki = 3.5 nM). In mouse colonic epithelia, 1-EBIO also activates cAMP-sensitive K+ channels, a response this is inhibited by 293B.In this type of epithelium, but not mouse nasal epithelia, 1-EBIO activates both types of channels, resulting in large Cl- secretory currents.It also activates the human intermediate conductance Ca2+-activated K+ channel (EC50 = 74 μM).1-EBIO is currently used to study the role of these types of K+ channels in diverse physiological functions.
使用
1-EBIO stimulates Cl- secretion in secretory epithelia through direct activation of clacium potassium channels.
1-EBIO was used to study the electrical activity modulated by Ca+2-activated K+ channels in rat central neurons. The effect of 1-EBIO on human intermediate conductance channels was studied.
The K+ channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients
生物活性
Activator of epithelial K Ca channels, stimulates a large and sustained trans-epithelial Cl - secretory response across T84 monolayers. Induces hyperpolarization to the same magnitude as ACh in aortic value endothelial cells.
1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン 上流と下流の製品情報
原材料
準備製品
1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン 生産企業
Global( 104)Suppliers
1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン スペクトルデータ(1HNMR)
10045-45-1(1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン)キーワード:
- 10045-45-1
- 1-Ethyl-1H-benzimidazole-2(3H)-one
- 1-Ethyl-2,3-dihydro-1H-benzimidazole-2-one
- EBIO
- 1-Ethyl-2-benzimidazolinone,98%
- Einecs 233-148-1
- 1-EB10
- 1-ethyl-1,3-dihydro-2H-benzimidazol-2-one(SALTDATA: FREE)
- 1-EBIO, 1-Ethyl-2-benzimidazolinone
- 1-Ethyl-1H-benzo[d]iMidazol-2(3H)-one
- 1-EthylbenziMidazolinone
- 1-ETHYL-2-BENZIMIDAZOLINONE
- 1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE
- 1-EBIO
- 1-Ethyl-2-benzimidazolineone
- 1-ethylbenzimidazolin-2-one
- 1-ETHYL-2-BENZCMIDAZOLINONE
- 2H-Benzimidazol-2-one,1-ethyl-1,3-dihydro-(9CI)
- 3-ethyl-1H-benzimidazol-2-one
- 2H-Benzimidazol-2-one, 1-ethyl-1,3-dihydro-
- 1-Ethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one
- 1-エチル-2-ベンゾイミダゾリノン
- 1-エチル-1,3-ジヒドロ-2H-ベンゾイミダゾール-2-オン
- 1-エチル-1H-ベンゾイミダゾール-2(3H)-オン
- 1-エチル-2,3-ジヒドロ-1H-ベンゾイミダゾール-2-オン
- 1-エチル-1,3-ジヒドロ-2H-ベンズイミダゾール-2-オン
- 1-エチルベンズイミダゾリノン
- 1-EBIO
- 1-エチル-2,3-ジヒドロ-1H-1,3-ベンゾジアゾール-2-オン