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ミゾラスチン

ミゾラスチン 化学構造式
108612-45-9
CAS番号.
108612-45-9
化学名:
ミゾラスチン
别名:
ミゾラスチン;ミゾラスチン (JAN)
英語化学名:
Mizolastine
英語别名:
MKC 431;Mizollen;Zolistan;SL 850324;MistaMine;MIZOLASTINE;Mizolastine HCl;Mizolastine inn;Mizolastine, >=99%;Mizolastine (Mizollen)
CBNumber:
CB7150058
化学式:
C24H25FN6O
分子量:
432.49
MOL File:
108612-45-9.mol

ミゾラスチン 物理性質

融点 :
217°
比重(密度) :
1.34±0.1 g/cm3(Predicted)
酸解離定数(Pka):
9.73±0.40(Predicted)
Merck :
14,6221

安全性情報

RTECS 番号 UW7481284

ミゾラスチン 価格 もっと(11)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQA-6323 ミゾラスチン
Mizolastine
108612-45-9 1g ¥28800 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01COBQA-6323 ミゾラスチン
Mizolastine
108612-45-9 5g ¥86400 2018-12-26 購入
東京化成工業 M2756 ミゾラスチン >98.0%(HPLC)(T)
Mizolastine >98.0%(HPLC)(T)
108612-45-9 5g ¥38900 2018-12-04 購入
東京化成工業 M2756 ミゾラスチン >98.0%(HPLC)(T)
Mizolastine >98.0%(HPLC)(T)
108612-45-9 1g ¥11200 2018-12-04 購入
富士フイルム和光純薬株式会社(wako) W01TRCM385400 ミゾラスチン
Mizolastine
108612-45-9 50mg ¥16300 2018-12-26 購入

ミゾラスチン 化学特性,用途語,生産方法

効能

抗アレルギー薬, H1受容体拮抗薬

説明

Mizolastine was marketed in Germany and Switzerland as Mizollen for the symptomatic relief of seasonal and perennial allergic rhinoconjunctivitis and urticaria. Mizolastine is a new long-acting, orally active antihistaminic agent with a rapid onset of action ; the two most recent H1 antagonists launched were fexofenadine, metabolite of terfenadine (Sepracor, 1996) and Olopatadine (Kyowa Hakko, 1997). Mizolastine can be prepared in 2 steps from 2-chloro 1- (4-fluorobenzyl)benzimidazole by successive condensations of appropriate amine and thioether. Mizolastine selectively blocks the peripheral H1 receptors (but not the serotonergic, noradrenergic, muscarinic receptors) with a minimal occupancy of brain receptors, and therefore does not elicit any sedative effects. Moreover, Mizolastine does not produce cardiac rhythm disorders which have been associated with certain non-sedating antihistamines in humans.

化学的特性

White Solid

Originator

Synthelabo (France)

使用

A highly selective histamine H1-receptor antagonist (with no anticholinergic, antiadrenergic, or antiserotonin activity) for use in the treatment of allergic disorders, especially rhinitis and urticaria.

使用

Allergic rhinitis;Blocking H1 receptors

brand name

Mizollen

ミゾラスチン 上流と下流の製品情報

原材料

準備製品


ミゾラスチン 生産企業

Global( 165)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21806 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22631 55
Liaoning Benyuan Pharmaceutical Co., Ltd
024-45627555
024-45627566 sales@benyuanpharm.com China 62 50
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23978 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6372 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23048 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47484 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 127809 58
Mainchem Co., Ltd. +86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32445 55
J & K SCIENTIFIC LTD. 400-666-7788 010-82848833-
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76

108612-45-9(ミゾラスチン)キーワード:


  • 108612-45-9
  • 2-[[1-[1-[(4-fluorophenyl)methyl]-2-benzimidazolyl]-4-piperidinyl]-methylamino]-1H-pyrimidin-6-one
  • MistaMine
  • Mizollen
  • MKC 431
  • SL 850324
  • Zolistan
  • 4(3H)-PyriMidinone,2-[[1-[1-[(4-fluorophenyl)Methyl]-1H-benziMidazol-2-yl]-4-piperidinyl]MethylaMino]-
  • 2-((1-(1-(4-Fluorobenzyl)-1H-benzo[d]iMidazol-2-yl)piperidin-4-yl)(Methyl)aMino)pyriMidin-4(1H)-one
  • 2-((1-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-piperidin-4-yl)(methyl)amino)pyrimidin-4(1H)-
  • Mizolastine (Mizollen)
  • Mizolastine, >=99%
  • 2-[{1-[1-(4-fluorobenzyl)-1H-benzimidazol-2-yl]piperidin-4-yl}(methyl)amino]pyrimidin-4(1H)-one
  • 2-((1-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-piperidin-4-yl)(methyl)amino)pyrimidin-4(1
  • Mizolastine 4(1h)-pyrimidinone,2-((1-(1-((4-fluorophenyl)methyl)-1h-benzimidazol-2-yl)-4-p
  • 4(1h)-pyrimidinone,2-((1-(1-((4-fluorophenyl)methyl)-1h-benzimidazol-2-yl)-4-p
  • iperidinyl)methylamino)-
  • 2-[[1-[1-[(4-fluorophenyl)methyl]benzoimidazol-2-yl]-4-piperidyl]-methyl-amino]-3h-pyrimidin-4-one
  • MIZOLASTINE
  • 2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(1H)-pyrimidinone
  • Mizolastine HCl
  • 2-[[1-[1-(4-fluorobenzyl)benzimidazol-2-yl]-4-piperidyl]-methyl-amino]-1H-pyrimidin-6-one
  • 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methyl-amino]-1H-pyrimidin-6-one
  • 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one
  • Mizolastine inn
  • ミゾラスチン
  • ミゾラスチン (JAN)
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