3'-クロロプロピオフェノン
3'-クロロプロピオフェノン 物理性質
- 融点 :
- 45-47 °C(lit.)
- 沸点 :
- 124 °C14 mm Hg(lit.)
- 比重(密度) :
- 1.1115 (rough estimate)
- 屈折率 :
- 1.5350 (estimate)
- 闪点 :
- >230 °F
- 貯蔵温度 :
- Sealed in dry,Room Temperature
- 溶解性:
- メタノールに可溶。
- 外見 :
- 結晶性固体
- 色:
- 白色～淡黄色
- InChI:
- InChI=1S/C9H9ClO/c1-2-9(11)7-4-3-5-8(10)6-7/h3-6H,2H2,1H3
- InChIKey:
- PQWGFUFROKIJBO-UHFFFAOYSA-N
- SMILES:
- C(C1=CC=CC(Cl)=C1)(=O)CC
- LogP:
- 3.041
- CAS データベース:
- 34841-35-5(CAS DataBase Reference)
3'-クロロプロピオフェノン 価格
もっと(20)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01AFAA12542 |
3'-クロロプロピオフェノン, 98%
3'-Chloropropiophenone, 98% |
34841-35-5 |
100g |
￥34250 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01AFAA12542 |
3'-クロロプロピオフェノン, 98%
3'-Chloropropiophenone, 98% |
34841-35-5 |
500g |
￥146010 |
2024-03-01 |
購入 |
|
東京化成工業
|
C2033 |
3'-クロロプロピオフェノン >98.0%(GC)
3'-Chloropropiophenone
>98.0%(GC) |
34841-35-5 |
25g |
￥3700 |
2024-03-01 |
購入 |
|
東京化成工業
|
C2033 |
3'-クロロプロピオフェノン >98.0%(GC)
3'-Chloropropiophenone
>98.0%(GC) |
34841-35-5 |
250g |
￥16500 |
2024-03-01 |
購入 |
|
関東化学株式会社(KANTO)
|
27658-2A |
３′‐クロロプロピオフェノン 98%
3′‐Chloropropiophenone 98% |
34841-35-5 |
250g |
￥22400 |
2024-03-01 |
購入 |
3'-クロロプロピオフェノン 化学特性,用途語,生産方法
外観
白色～微褐色の結晶又は結晶性粉末
用途
有機合成原料。
説明
Influence of solvents and temperature on the yield and enantioselectivity of the phenylation of 3′-chloropropiophenone has been investigated.
化学的特性
WHITE TO LIGHT YELLOW CRYSTALLINE SOLID
使用
3'-Chloropropiophenone is a reagent used in the vinylation, alkylation and dienylation of ketones. It is also used in the preparation of thizaine derivatives that show antibacterial activity.
主な応用
3′-Chloropropiophenone can be used as a reactant to synthesize:
(S)-3-chloro-1-phenylpropanol via bio-catalyzed asymmetric reduction method.
1-(3-Chlorophenyl)-1-phenyl-1-propanol by phenylation with diphenylzinc in the presence of dihydroxy bis(sulfonamide) ligand.
(S)-Dapoxetine, a selective serotonin reuptake inhibitor.
製造方法
4.86 g (0.2 mol) of magnesium turnings, 30 ml of dry diethyl ether and a grain of iodine are placed in a one liter three-necked round-bottomed flask equipped with a condenser, a calcium chloride drying tube, a pressure equalizing funnel and a magnetic stirrer; the flask is purged with nitrogen, and 21.8 g (0.2 mol) of ethyl bromide in 30 ml of dry diethyl ether are then added. The mixture is then heated under reflux for one hour and left to cool. At ambient temperature, 16.51 g (0.12 mol) of 3-chlorobenzonitrile in 70 ml of dry diethyl ether are then added. A copious precipitate forms. The mixture is stirred overnight at ambient temperture and then cooled in an ice bath and hydrolysed by slowly adding 50 ml of water and then about 100 ml of 6N hydrochloric acid until the pH is acid. The mixture is stirred for one and a half hours and then extracted with ethyl acetate. The organic extract is then washed twice with water, dried and concentrated on a rotary evaporator. This gives 26 g of an orange oil, which is concentrated in vacuo to give about 18.2 g of ochre crystals of 3'-chloropropiophenone melting at about 40° C.
Literature source US04690931
3'-クロロプロピオフェノン 上流と下流の製品情報
原材料
準備製品
3'-クロロプロピオフェノン 生産企業
Global( 522)Suppliers
| 名前 |
電話番号 |
電子メール |
国籍 |
製品カタログ |
優位度 |
|
Hebei Guanlang Biotechnology Co,.LTD
|
+8619930503252
|
daisy@crovellbio.com |
China |
5964 |
58 |
|
Jinan Qinmu Fine Chemical Co.,Ltd.
|
+8618660799346
|
sales@qinmuchem.com |
China |
1009 |
58 |
|
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
|
+8617731987558
|
xingjiu@xingjiubiotech.com |
China |
990 |
58 |
|
Nanjing Deda New Material Technology Co., Ltd
|
+8613223293093
|
bella@njdeda.com |
China |
81 |
58 |
|
Hebei Mojin Biotechnology Co., Ltd
|
+8613288715578
|
sales@hbmojin.com |
China |
12453 |
58 |
|
Henan Fengda Chemical Co., Ltd
|
+86-371-86557731 +86-13613820652
|
info@fdachem.com |
China |
7534 |
58 |
|
Hunan aslsen technology co.,ltd
|
+8619310186019
|
aslsb@aslsen.com |
China |
124 |
58 |
|
Capot Chemical Co.,Ltd.
|
571-85586718 +8613336195806
|
sales@capotchem.com |
China |
29797 |
60 |
|
Shanghai Daken Advanced Materials Co.,Ltd
|
+86-371-66670886
|
info@dakenam.com |
China |
15371 |
58 |
|
Shanghai Bojing Chemical Co.,Ltd.
|
+86-86-02137122233 +8613795318958
|
bj1@bj-chem.com |
China |
298 |
55 |
3'-クロロプロピオフェノン スペクトルデータ(1HNMR、13CNMR、IR1、IR2、MS、Raman)
34841-35-5(3'-クロロプロピオフェノン)キーワード:
- 34841-35-5
- 3-CHLOROPHENYL ETHYL KETONE
- (3-CHLOROPHENYL)PROPAN-1-ONE
- 1-(3-CHLOROPHENYL)-1-PROPANONE
- 3-CHLORO-1-PHENYL-PROPANONE
- 3-CHLOROPROPIOPHENONE M-CHLORO PROPIOPHENONE
- 3-Chloro-Propiophenone(M-ChloroProiophenone)
- M-ChloroProiophenone
- 3'-Chloropropiophenone
- 3'-Chloropropiopheno
- Between chloropropiophenone
- 1-Propanone, 1-(3-chlorophenyl)-
- Bupropion Des-t-ButylaMino IMpurity
- 3&priMe
- 3'-chloroacetone
- ：3’-Chloropropiophenone，1-(3-chlorophenyl)propan-1-one
- 3 '- chlorobenzene acetone
- 3'-Chloropropiophenone Synonyms 1-(3-Chlorophenyl)-1-propanone
- 3'-Chloropropiophenone, 97+%
- Bupropion Hydrochloride Impurit Ⅰ： 3'-Chloropropiophenone
- Bupropion Impurity 14 (3'-Chloropropiophenone)
- Bupropion Impurity 22
- Bupropion Hydrochloride Impurity Ⅰ（3-chloropropiophenone）
- Chloropropiophenone Chloropropiophenone
- MCPP
3'-Chloropropiophenone
- 3'-Chloropropiophenone USP/EP/BP
- 3'-Chloropropiophenone/META CHLOROPROPIOPHENONE
- 3’-ChloropropiophenoneQ: What is
3’-Chloropropiophenone Q: What is the CAS Number of
3’-Chloropropiophenone Q: What is the storage condition of
3’-Chloropropiophenone Q: What are the applications of
3’-Chloropropiophenone
- 1-(3-Chlorphenyl)propan-1-on
- Bupropion Hydrochloride Impurit Ⅰ： 3'-Chloropropiophenone
- M-CHLOROPROPIOPHENONE
- 3'-クロロプロピオフェノン
- 3’クロロプロピオフェノン
- 3′-クロロプロピオフェノン
- 3-クロロフェニルエチルケトン
- 3′‐クロロプロピオフェノン
- M-クロロプロピオフェノン
- 3'-クロロプロピオフェノン, 98%
- 1-(3-クロロフェニル)プロパン-1-オン
- 1-クロロ-3-プロパノイルベンゼン