(R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン

(R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン 価格 もっと(2)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01FLC212988	(R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one	173140-90-4	250mg	￥82500	2021-03-23	購入
富士フイルム和光純薬株式会社(wako)	W01FLC212988	(R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one	173140-90-4	1g	￥246300	2021-03-23	購入

(R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン 化学特性,用途語,生産方法

使用

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

合成

A 5 liter flask equipped with a mechanical stirrer, thermometer, and refluxing condenser was charged with 8-benzyloxy-5-[(R)-(2-bromo-1-hydroxyethyl)]-carbostyriI (70gms/0.187 moles), potassium carbonate (74 gmsl 0.536 moles), acetone (3.5 liters) and water (35 ml). The resulting slurry 'was heated to reflux and maintained for 2% hours. After completion of reaction, the hot mass was filtered on hylo bed to remove inorganics. The residue was slurried in dichloromethane (200 ml) and filtered on hyflo bed. The filtrates were combined together and concentrated under vacuum completely. The residue was dissolved. in dichloromethane (500ml) and filtered on hyflo bed to remove traces of insolubles and washed with dichloromethane(100 ml). The clear filtrate was distilled completely to obtain residue. The residue was charged with methanol (70 ml), stirred and heated to 50??C for 30 minutes. The slurry obtained was cooled to 25-30??C,chilled to 0- 5??C, stirred for 1 hour. The resulting solid was isolated by filtration, washed with methanol (30ml), followed by diisopropylether (100ml) and dried under vacuum at 60-65 ??C for 10-12 hours to yield 40-41 gms of 8-benzyloxy- 5-(R)-oxiranylcarbostyril.

(R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン 上流と下流の製品情報

原材料

準備製品

(R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
BIONNA MEDICINE CO.,LTD	01056380788-8515; +8618518759099	790226113@qq.com	China	52	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2141	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2967	58

173140-90-4((R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン)キーワード:

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• 173140-90-4
• 2(1H)-Quinolinone, 5-(2R)-oxiranyl-8-(phenylmethoxy)-
• 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
• Indacaterol interMediate :2 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
• 8-(Benzyloxy)-5-[(2R)-oxiran-2-yl]quinolin-2(1H)-one
• 2 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone
• 8-benzoxy-5-(R)-oxiranyl-1H-quinolin-2-one
• (R)-5-(2-oxiranyl)-8-benzyloxy-2(1H)-quinolinone
• BNKY004-IM01
• 5-[(2R)-oxiran-2-yl]-8-phenylmethoxy-1H-quinolin-2-one
• 2(1H)-Quinolinone, 5-(2R)-2-oxiranyl-8-(phenylmethoxy)-
• 8-(benzyloxy)-5-((1R)-2-((5-ethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one fumarate
• (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one( Indacaterol Impurity 5)
• (R)-8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one
• 5-(2R)-2-Oxiranyl-8-(phenylmethoxy)-2(1H)-quinolinone
• 5- (2R) -2-epoxyethanyl-8-benzyloxy-2 (1H) - quinolone
• 5-(2R) -2-epoxyl-8-benzoxy-2 (1H) -quinolone
• (R)-8-(ベンジルオキシ)-5-(オキシラン-2-イル)キノリン-2(1H)-オン