3,4-ジメトキシベンズアルデヒド 化学特性,用途語,生産方法
外観
白色～うすい赤色～緑色粉末～結晶
溶解性
エタノール及びアセトンに極めて溶けやすく、水に極めて溶けにくい。
用途
香料,合成中間
化学的特性
Veratraldehyde is a crystalline solid (mp 44.5–45°C) with a woody, vanillalike
odor.
Veratraldehyde can be prepared by methylation of vanillin. It is used in oriental
and warm, woody fragrances, as well as in flavor compositions for vanilla notes. It
is an intermediate in, for example, the synthesis of pharmaceuticals.
天然物の起源
Reported among the constituents of the essential oils of Cymbopogon javanensis and Eryngium poterium. Also
reported found in raspberry, ginger, peppermint oil, Bourbon vanilla and mastic gum oil.
使用
Veratraldehyde was used in the preparation of 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane. It was used in the synthesis of (+)-lithospermic acid, having anti-HIV activity. It forms 1:1 inclusion complexes with cyclodextrins. It reacts with 3-acetyl-2,5-dimethythiophene to yield chalcone dye, (2E)-3-(3,4-Dimethoxyphenyl)-1-(2,5-dimethylthiophen-3-yl)prop-2-en-1-one.
製造方法
Prepared from vanillin by methylation of vanillin with dimethylsulfate under mildly alkaline conditions.
一般的な説明
Needles or chunky light peach powder. Has an odor of vanilla beans.
空気と水の反応
Insoluble in water.
反応プロフィール
Veratraldehyde is incompatible with strong oxidizing agents and strong bases. . Veratraldehyde is an aldehyde. Aldehydes are readily oxidized to give carboxylic acids. Flammable and/or toxic gases are generated by the combination of aldehydes with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents. Aldehydes can react with air to give first peroxo acids, and ultimately carboxylic acids. These autoxidation reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by the products of the reaction).
火災危険
Veratraldehyde is probably combustible.
純化方法
Crystallise the ether from diethyl ether, pet ether, CCl4 or toluene. [Beilstein 8 IV 1765.]
3,4-ジメトキシベンズアルデヒド 上流と下流の製品情報
原材料
準備製品
6,7-Dimethoxy-2,4-Quinazolinedione
B-(3,4-DIMETHOXYPHENYL)-A-CYANOPROPIONALDEHYDE DIMETHYLACETAL
ジアベリジン
7-ヒドロキシ-6-メトキシ-3,4-ジヒドロイソキノリン
3,4-ジメトキシフェニルアセトン
3-フェニルウンベリフェロン
ホモベラトル酸
メチルドーパ
フェノルドパム
ベラトリルアルコール
3,4-ジヒドロキシフェニル酢酸
2-(3,4-ジメトキシフェニル)-5,6,7-トリメトキシ-4H-1-ベンゾピラン-4-オン
2,6-Bis-(3,4-Dimethoxyphenylmethylene)-Cyclohexanone