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アラキドニル-2-クロロエチルアミド

アラキドニル-2-クロロエチルアミド 化学構造式
220556-69-4
CAS番号.
220556-69-4
化学名:
アラキドニル-2-クロロエチルアミド
别名:
アラキドニル-2-クロロエチルアミド;アラキドニル-2′-クロロエチルアミド 水和物
英語化学名:
ACEA
英語别名:
ACEA;2'-CHLORO-AEA;ACEA (ethanol solution);ARACHIDONYL-2-CHLOROETHYLAMIDE;ARACHIDONYL-2'-CHLOROETHYLAMIDE;ARACHIDONOYL 2'-CHLOROETHYLAMIDE;ARACHIDONYL-2'-CHLOROETHYLAMIDE HYDRATE;N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;(5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)-5,8,11,14-eicosatetraenaMide
CBNumber:
CB7484072
化学式:
C22H36ClNO
分子量:
365.98
MOL File:
220556-69-4.mol

アラキドニル-2-クロロエチルアミド 物理性質

RTECS 番号:
JX3840800
貯蔵温度 :
−20°C
溶解性:
DMSO: soluble
外見 :
oil
色:
pale yellow
Sensitive :
Air Sensitive

安全性情報

WGK Germany  3

アラキドニル-2-クロロエチルアミド 価格 もっと(8)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01CAY91054
Arachidonoyl 2'-Chloroethylamide
220556-69-4 5mg ¥6400 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01CAY91054
Arachidonoyl 2'-Chloroethylamide
220556-69-4 10mg ¥12200 2018-12-26 購入
Sigma-Aldrich Japan A9719 アラキドニル-2′-クロロエチルアミド 水和物 ≥97% (HPLC), oil
Arachidonyl-2′-chloroethylamide hydrate ≥97% (HPLC), oil
220556-69-4 25mg ¥70800 2018-12-25 購入
富士フイルム和光純薬株式会社(wako) W01TOC1319
ACEA
220556-69-4 25mg ¥78000 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01TRCA765020 アラキドニル-2-クロロエチルアミド
Arachidonyl-2-chloroethylamide
220556-69-4 50mg ¥300000 2018-12-26 購入

アラキドニル-2-クロロエチルアミド 化学特性,用途語,生産方法

使用

A synthetic agonist of the cannabinoid receptor 1 (CB1R). ACEA is considered to be a selective cannabinoid agonist as it binds primarily to the CB1R and has low affinity to the cannabinoid receptor 2 (CB2R).

生物活性

Potent and highly selective CB 1 receptor agonist (K i = 1.4 nM). Displays > 1400-fold selectivity over CB 2 receptors. Active in vivo . Also available as part of the Cannabinoid CB 1 Receptor Tocriset™ .

酵素阻害剤

This synthetic CB1 receptor agonist and anandamide (N- arachidonylethanolamide) analogue (FW = 365.99 g/mol; CAS 220556-69-4; Symbol: ACEA) is a selective agonist of cannabinoid receptor-1 (Ki = 1.4 nM) but has low affinity to the cannabinoid receptor 2 (Ki = 3.1 μM). ACEA inhibits forskolin-induced cAMP accumulation in Chinese hamster ovary cells expressing the human CB1 receptor. It also increases the binding of [ 35 S]GTPgS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. ACEA produces hypothermia in mice, an effect that is inhibited by co-administration of the CB1 receptor antagonist SR141716A.

酵素阻害剤

This synthetic CB1 receptor agonist and anandamide (N- arachidonylethanolamide) analogue (FW = 365.99 g/mol; CAS 220556-69-4; Symbol: ACEA) is a selective agonist of cannabinoid receptor-1 (Ki = 1.4 nM) but has low affinity to the cannabinoid receptor 2 (Ki = 3.1 μM). ACEA inhibits forskolin-induced cAMP accumulation in Chinese hamster ovary cells expressing the human CB1 receptor. It also increases the binding of [ 35 S]GTPgS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. ACEA produces hypothermia in mice, an effect that is inhibited by co-administration of the CB1 receptor antagonist SR141716A.

アラキドニル-2-クロロエチルアミド 上流と下流の製品情報

原材料

準備製品


アラキドニル-2-クロロエチルアミド 生産企業

Global( 22)Suppliers
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220556-69-4(アラキドニル-2-クロロエチルアミド)キーワード:


  • 220556-69-4
  • N-(2-CHLOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE
  • ARACHIDONYL-2'-CHLOROETHYLAMIDE
  • ARACHIDONYL-2-CHLOROETHYLAMIDE
  • ARACHIDONOYL 2'-CHLOROETHYLAMIDE
  • ACEA
  • 2'-CHLORO-AEA
  • ARACHIDONYL-2'-CHLOROETHYLAMIDE HYDRATE
  • ACEA (ethanol solution)
  • (5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)-5,8,11,14-eicosatetraenaMide
  • アラキドニル-2-クロロエチルアミド
  • アラキドニル-2′-クロロエチルアミド 水和物
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