シプロヘプタジン
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- CAS番号.
- 129-03-3
- 化学名:
- シプロヘプタジン
- 别名:
- 4-(5H-ジベンゾ[a,d]シクロヘプテン-5-イリデン)-1-メチルピペリジン;ペリアクチン;4-[5H-ジベンゾ[a,d]シクロヘプテン-5-イリデン]-1-メチルピペリジン;シプロヘプタジン;5-(1-メチルピペリジン-4-イリデン)-5H-ジベンゾ[a,d]シクロヘプテン;ペリアクチノール;サイプロヘプタジン;1-メチル-4-{トリシクロ[9.4.0.03,8]ペンタデカ-1(15),3,5,7,9,11,13-ヘプタエン-2-イリデン}ピペリジン
- 英語名:
- Cyproheptadine
- 英語别名:
- Periactin;MK 141;Dronactin;Periactine;Periactinol;Cypoheptadine;AKOS NCG1-0040;CYPROHEPTADINE;Eiproheptadine;Cycloheptadine
- CBNumber:
- CB7782550
- 化学式:
- C21H21N
- 分子量:
- 287.4
- MOL File:
- 129-03-3.mol
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シプロヘプタジン 物理性質
- 融点 :
- 112.3-113.3°
- 沸点 :
- 419.7°C (rough estimate)
- 比重(密度) :
- 0.9917 (rough estimate)
- 屈折率 :
- 1.8240 (estimate)
- 貯蔵温度 :
- Store at -20°C
- 酸解離定数(Pka):
- pKa 8.87 (Uncertain)
- 色:
- EtOH (aq) からの結晶
- 水溶解度 :
- 317.6ug/L(22.5℃)
- CAS データベース:
- 129-03-3(CAS DataBase Reference)
- NISTの化学物質情報:
- Cyproheptadine(129-03-3)
シプロヘプタジン 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
シプロヘプタジン 化学特性,用途語,生産方法
効能
抗アレルギー薬, H1受容体拮抗薬
説明
Cyproheptadine has antianaphylactic activity that is associated with its ability to slow
down the release of histamine and other mediators from fat cells.
使用
Antihistaminic; antipruritic.
定義
ChEBI: The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments.
t is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and food
, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
世界保健機関（WHO）
Cyproheptadine, an antihistamine with anticholinergic and
serotonin-antagonist properties, was introduced in 1961 for the symptomatic relief
of allergy and was subsequently used as an appetite stimulant. In 1982 the drug
was prohibited in Bangladesh because of its misuse as an appetite stimulant due
to inappropriate promotion. Cyproheptadine remains widely available and the
current marketing policy of the major manufacturer requires that it should be used
as an appetite stimulant only under the supervision of a physician who should be
assured that adequate food is available.
安全性プロファイル
Poison by ingestion, intraperitoneal, subcutaneous and intravenous routes. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
シプロヘプタジン 上流と下流の製品情報
原材料
準備製品
シプロヘプタジン 生産企業
Global( 63)Suppliers
129-03-3(シプロヘプタジン)キーワード:
- 129-03-3
- 1-Methyl-4-(5H-dibenzo[a,d]cycloheptenylidene)piperidine
- Cypoheptadine
- Cyproheptadiene
- Dronactin
- Eiproheptadine
- MK 141
- Periactine
- Periactinol
- Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-
- CYPROHEPTADINE
- AKOS NCG1-0040
- 4-dibenzo(a,d)cycloepten-5-ylidene-1-methylpiperidine
- 5-[1-Methylpiperidylidene-4]-[5H]-dibenzo [a,d] cycloheptene
- DIBENZOSUBERONONE /CYPROHEPTADINE
- 1-Methyl-4-(dibenzo[a,e]cycloheptatrien-5-ylidene)piperidine
- 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
- Cycloheptadine
- TIANFUCHEM--129-03-3--Cyproheptadine in stock
- Periactin
- Cyproheptadine HCl IP/BP/Ph. Eur /USP
- Cyproheptadine in methanol
- 4-(5H-ジベンゾ[a,d]シクロヘプテン-5-イリデン)-1-メチルピペリジン
- ペリアクチン
- 4-[5H-ジベンゾ[a,d]シクロヘプテン-5-イリデン]-1-メチルピペリジン
- シプロヘプタジン
- 5-(1-メチルピペリジン-4-イリデン)-5H-ジベンゾ[a,d]シクロヘプテン
- ペリアクチノール
- サイプロヘプタジン
- 1-メチル-4-{トリシクロ[9.4.0.03,8]ペンタデカ-1(15),3,5,7,9,11,13-ヘプタエン-2-イリデン}ピペリジン
- セロトニン拮抗薬
- ヒスタミンＨ１受容体遮断薬