1,3-ジアミノプロパン 化学特性,用途語,生産方法
外観
無色～ほとんど無色, 澄明の液体
溶解性
水, アルコールに易溶。エタノール、エーテル、クロロホルム、ベンゼンに混ざる。水及びエタノールに極めて溶けやすい。
解説
1,3-propanediamine．C3H10O2(74.13)．H2N(CH2)3NH2．臭化トリメチレンにアルコール性アンモニアを作用させると得られる．アンモニア臭をもつ液体．融点－22 ℃，沸点140 ℃．d420"0.888．nD20"1.459．K 3.5×10－4(25 ℃)．水，エタノール，ベンゼンに可溶．放置すると二酸化炭素を吸収する．ポリアミド，アニオン系洗剤のソフナー，木綿の加工用樹脂原料，架橋剤として用いられる．有毒で眼，粘膜，皮膚をおかす．LD50 350 mg/kg(ラット，経口)．[CAS 109-76-2]
森北出版「化学辞典（第2版）
用途
エポキシ樹脂硬化剤
化学的特性
colourless liquid
使用
1,3-Diaminopropane is commonly used in the preparation of cholinesterase inhibitors and thrombosis inhibitors. It is also used as a polymer cross linkage agent, polyurethane extender and spray coatings. It is involved in the preparation of agrochemicals and pharmaceutical intermediates. Further, it acts as a building block in the synthesis of heterocyclic compounds, which finds application in textile finishing. In addition to this, it is used as a ligand and form coordination complexes. 1,3-Diaminopropane is also utilized for the production of a chelating agent used in the photo industry and for anticorrosion agents.
調製方法
1,3-Diaminopropane is produced in a twostage continuous process, under a pressure of 10 – 20 MPa. In a first reactor, acrylonitrile reacts with excess ammonia at 70 – 100 ℃ to give 2-aminopropionitrile and bis(cyanoethyl) amine. The mixture of aminonitriles is then hydrogenated in a downstream reactor over a fixed-bed catalyst (cobalt or nickel) at 60 – 120 ℃ to give 1,3-diaminopropane and bis (aminopropyl)amine. The yield of 1,3- diaminopropane can be increased by adding a polar solvent and water or by using a large excess of ammonia.
定義
ChEBI: An alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3.
一般的な説明
Water-white mobile liquid with an odor of amine.
空気と水の反応
Highly flammable. Water soluble.
反応プロフィール
1,3-Diaminopropane is heat sensitive. 1,3-Diaminopropane may react with oxidizing agents.
健康ハザード
ACUTE/CHRONIC HAZARDS: 1,3-Diaminopropane is a strong irritant to eyes and skin: corrosive HAZARDOUS DECOMPOSITION PRODUCTS.
火災危険
1,3-Diaminopropane is a flammable liquid.
安全性プロファイル
Poison by ingestion and
skin contact. Experimental teratogenic
effects. A severe skin and eye irritant.
Flammable liquid when exposed to heat,
sparks, or flame. When heated to
decomposition it emits toxic fumes of NOx.
See also AMINES.
1,3-ジアミノプロパン 上流と下流の製品情報
原材料
準備製品
rac-2β*-(2-メチルベンジルオキシ)-4α*-イソプロピル-1α*-メチル-7-オキサビシクロ[2.2.1]ヘプタン
N-(tert-ブトキシカルボニル)-1,2-ジアミノエタン
Cocoamidopropyl betaine
dihydroxyethyl p-octadecyl phenylsulfonyl amino propyl ammoium propylsulfonate
ホモピペラジン
N-(tert-ブトキシカルボニル)-1,3-ジアミノプロパン
Propanenitrile, 3-[(3-aminopropyl)amino]-
2,3,4,5-テトラヒドロ-1H-1,5-ベンゾジアゼピン
3,3'-[(プロパン-1,3-ジイル)ビスイミノ]ビス(プロパン-1-アミン)
2-(3,4-ジメチルフェニル)ピリジン