インターフェロン　ベータ－1b（遺伝子組換え）

インターフェロン　ベータ－1b（遺伝子組換え） 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

インターフェロン　ベータ－1b（遺伝子組換え） 化学特性,用途語,生産方法

説明

Interferon β-1b, a stable analog of human interferon-βproduced by recombinant DNA technique, is the first biotechnology product to be licensed under the FDA's accelerated approval regulation. It is the first drug available for the treatment of relapsing remitting multiple sclerosis (MS). The mechanism of action of interferon β-1b in MS remains unknown. It has shown immunoregulatory properties including its ability to decrease T-cell proliferation, to block the synthesis of interferonγthat may be involved in MS, to inhibit release of other cytokines that damage oligodendrocytes, and to increase T suppresser-cell activity. Interferonβ-1b has also demonstrated potential in melanoma, renal cell carcinoma, genital warts, hepatitis, rhinovirus, and several types of malignant tumors.

使用

Immunomodulator.

一般的な説明

Interferon beta-1b, Betaseron, is a protein that is expressedin a recombinant E. coli. It is equivalent in type to the interferonthat is expressed by human fibroblasts. In addition to its antiviralactivity, interferon beta-1b possesses immunomodulatingactivity.Interferon beta-1b is administered SC to decrease the frequencyof clinical exacerbation in ambulatory patients withrelapsing–remitting multiple sclerosis (RRMS). RRMS ischaracterized by unpredictable attacks resulting in neurologicaldeficits, separated by variable periods of remission.Although it is not possible to delineate the mechanismsby which interferon beta-1b exerts its activity in MS, it isknown that the interferon binds to specific receptors on cellsurfaces and induces the expression of several interferoninducedgene products, such as 2',5'-oligoadenylate synthetaseand protein kinase. Additionally, interferon beta-1bblocks the synthesis of INF-γ, which is believed to be involvedin MS attacks.

インターフェロン　ベータ－1b（遺伝子組換え） 上流と下流の製品情報

原材料

準備製品

インターフェロン　ベータ－1b（遺伝子組換え） 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shanghai Boyle Chemical Co., Ltd.	021-50182298 021-50180596	sales@boylechem.com	China	2210	55
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12338	58

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• 145155-23-3
• interferon beta-1b
• Interferon β-1b (Human Recombinant)
• 17-L-Serine-2-166-interferon beta1 (human fibroblast reduced)
• Betaferon
• Betaseron
• Extavia
• Ziferon
• インターフェロン　ベータ－1b（遺伝子組換え）