4-(ピリジン-3-イル)ピリミジン-2-アミン
4-(ピリジン-3-イル)ピリミジン-2-アミン 物理性質
- 融点 :
- 189-191 °C
- 沸点 :
- 439.9±37.0 °C(Predicted)
- 比重(密度) :
- 1.259±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- under inert gas (nitrogen or Argon) at 2–8 °C
- 溶解性:
- DMSO（微量）、メタノール（微量）
- 外見 :
- 個体
- 酸解離定数(Pka):
- 2.76±0.10(Predicted)
- 色:
- オフホワイトからペールイエロー
- InChI:
- InChI=1S/C9H8N4/c10-9-12-5-3-8(13-9)7-2-1-4-11-6-7/h1-6H,(H2,10,12,13)
- InChIKey:
- LQHQKYWYKPLKCH-UHFFFAOYSA-N
- SMILES:
- C1(N)=NC=CC(C2=CC=CN=C2)=N1
4-(ピリジン-3-イル)ピリミジン-2-アミン 価格
もっと(12)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBST-1757 |
4-(3-Pyridinyl)-2-pyrimidine amine |
66521-66-2 |
1g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBST-1757 |
4-(3-Pyridinyl)-2-pyrimidine amine |
66521-66-2 |
5g |
￥35000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBST-1757 |
4-(3-Pyridinyl)-2-pyrimidine amine |
66521-66-2 |
100g |
￥375000 |
2024-03-01 |
購入 |
|
東京化成工業
|
P2666 |
4-(ピリジン-3-イル)ピリミジン-2-アミン >98.0%(GC)(T)
4-(Pyridin-3-yl)pyrimidin-2-amine
>98.0%(GC)(T) |
66521-66-2 |
1g |
￥7000 |
2024-03-01 |
購入 |
|
東京化成工業
|
P2666 |
4-(ピリジン-3-イル)ピリミジン-2-アミン >98.0%(GC)(T)
4-(Pyridin-3-yl)pyrimidin-2-amine
>98.0%(GC)(T) |
66521-66-2 |
5g |
￥24500 |
2024-03-01 |
購入 |
4-(ピリジン-3-イル)ピリミジン-2-アミン 化学特性,用途語,生産方法
外観
白色～うすい黄色～うすい黄赤色粉末～結晶
化学的特性
White to off-white or brown solid.
使用
4-(3-Pyridinyl)-2-pyrimidinamine serves as an intermediate compound during the synthesis of Nilotinib. Nilotinib is a selective tyrosine kinase receptor inhibitor used in the therapy of chronic myelogenous leukemia.
合成
3-(Dimethylamino)-1-(pyridine-3-yl) prop-2-en-1-one (15.4 g, 0.088 mol), guanidine nitrate (10.7 g, 0.088 mol), and sodium hydroxide (3.5 g, 0.088 mol) were dissolved in n-butanol (120 mL). The mixture was heated to reflux with stirring and maintained for 16 hours. The reaction mixture was then cooled to room temperature. The solid was collected and washed with water (400 mL). The desired product was dried under vacuum for three days, and 12.7 g of yellow crystals of 4-(Pyridin-3-yl)pyrimidin-2-amine was obtained (yield: 85 %).
4-(ピリジン-3-イル)ピリミジン-2-アミン 上流と下流の製品情報
原材料
準備製品
4-(ピリジン-3-イル)ピリミジン-2-アミン 生産企業
Global( 177)Suppliers
66521-66-2(4-(ピリジン-3-イル)ピリミジン-2-アミン)キーワード:
- 66521-66-2
- BUTTPARK 41\09-83
- 4-(3-PYRIDINYL)-2-PYRIMIDINAMINE
- 4-(3-PYRIDINYL)-2-PYRIMIDINE AMINE
- 4-(3-PYRIDINYL)-2-PYRIMIDINYLAMINE
- 4-(3-Pyridyl)-2-pyrimidinamine
- 4-(3-Pyridinyl)-2-aminopyrimidine
- 4-(3-Pyridyl)-2-pyrimidineamine
- 4-(3-Pyridinyl)-2-pyrimidine amine ,97%
- 2-amino-4-(3-pyridinyl)-pyrimidine
- 4-Pyridin-3-yl-pyriMidin-2-ylaMine
- 2-PyriMidinaMine,4-(3-pyridinyl)-
- 2-Amino-4-(3-pyridyl)pyrimidine
- 4-(3-piridinyl)-2-pirimidine amine
- 4-(3-Pyridinyl)-2-pyrimidine amine, 97%, reagent grade
- )-2-pyrimidine amine
- Nilotinib 3-Pyridinyl Impurity
- 4-(3-Pyridinyl)-2-aminopyrimidine ISO 9001：2015 REACH
- 4-(3-Pyridinyl)-2-aminopyrimidineQ: What is
4-(3-Pyridinyl)-2-aminopyrimidine Q: What is the CAS Number of
4-(3-Pyridinyl)-2-aminopyrimidine Q: What is the storage condition of
4-(3-Pyridinyl)-2-aminopyrimidine Q: What are the applications of
4-(3-Pyridinyl)-2-aminopyrimidine
- 4-(PYRIDIN-3-YL)PYRIMIDIN-2-AMINE
- 4-(ピリジン-3-イル)ピリミジン-2-アミン
- 4-(3-ピリジニル)-2-ピリミジンアミン
- 4-(3-ピリジル)ピリミジン-2-アミン
- 2-アミノ-4-(3-ピリジニル)ピリミジン
- 4-(3-ピリジニル)ピリミジン-2-アミン