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ロルカセリン塩酸塩

ロルカセリン塩酸塩 化学構造式
846589-98-8
CAS番号.
846589-98-8
化学名:
ロルカセリン塩酸塩
别名:
ロルカセリン塩酸塩
英語化学名:
(R)-1H-3-BENZAZEPINE,8-CHLORO-2,3,4,5-TETRAHYDRO-1-METHYL-,HYDROCHLORIDE
英語别名:
LORCASERIN HCL;(R)-1H-3-BENZAZEPINE;Lorcaserin hydrochloride;R Lorcaserin hydrochloride;Thiosildenafil Solution, 100ppm;Lorcaserin (hydrochloride) (CRM);Green Card mianserin hydrochloride;lorcaserin hydrochloride (APD-356);Lorcaserin Hydrochloride (>50% ee);LORCASERIN HCL;APD-356;APD356;APD 356
CBNumber:
CB82451004
化学式:
C11H15Cl2N
分子量:
0
MOL File:
846589-98-8.mol

ロルカセリン塩酸塩 物理性質

安全性情報

ロルカセリン塩酸塩 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

ロルカセリン塩酸塩 化学特性,用途語,生産方法

効能

食欲抑制薬, セロトニン5-HT2C受容体作動薬

説明

In June 2012, the US FDA approved lorcaserin for chronic weight management in adult patients who are characterized as overweight or obese and have at least one comorbid, weight-related condition. Lorcaserin (also known as APD356) is the first 5-HT2C agonist approved for chronic weight management since the withdrawal of the 5-HT2C agonist fenfluramine in 1997 due to rare cases of cardiac valvulopathy. The serotonin receptor 5-HT2C is found primarily in the hypothalamus and regulates appetite and feeding behavior. Safety issues with fenfluramine were associated with poor selectivity for 5-HT2C versus 5HT2A and 5HT2B. Ring constraint afforded by the benzazepine in lorcaserin improved selectivity for 5HT2C by over 2 log units.

Originator

Pharmaceuticals (United States)

使用

Anti-obesity (activate 5-HT2creceptor).

定義

ChEBI: A hydrochloride obtained by reaction of lorcaserin with one equivalent of hydrochloric acid. Used as an anti-obesity drug.

brand name

Belviq

ロルカセリン塩酸塩 上流と下流の製品情報

原材料

準備製品


ロルカセリン塩酸塩 生産企業

Global( 167)Suppliers
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846589-98-8(ロルカセリン塩酸塩)キーワード:


  • 846589-98-8
  • R Lorcaserin hydrochloride
  • lorcaserin hydrochloride (APD-356)
  • (R)-8-Chloro-1-Methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride
  • Lorcaserin Hydrochloride (>50% ee)
  • 1H-3-Benzazepine,8-chloro-2,3,4,5-tetrahydro-1-Methyl-, hydrochloride (1:1), (1R)-
  • Green Card mianserin hydrochloride
  • (R)-1H-3-BENZAZEPINE
  • Thiosildenafil Solution, 100ppm
  • Lorcaserin (hydrochloride) (CRM)
  • Lorcaserin hydrochloride, 98%, a selective full agonist of human 5-HT2C receptor
  • (R)-1H-3-BENZAZEPINE,8-CHLORO-2,3,4,5-TETRAHYDRO-1-METHYL-,HYDROCHLORIDE
  • (1R)-8-chloro-1-Methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
  • LORCASERIN HCL
  • Lorcaserin hydrochloride
  • (R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
  • LORCASERIN HCL;APD-356;APD356;APD 356
  • ロルカセリン塩酸塩
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