ゲミグリプチン

ゲミグリプチン 化学構造式
911637-19-9
CAS番号.
911637-19-9
化学名:
ゲミグリプチン
别名:
ゲミグリプチン
英語名:
GeMigliptin
英語别名:
LC15-0444;GeMigliptin;GeMigliptin WS;Gemigliptin - G10587;GeMigliptin Tartarate;Gemigliptin Hydrochloride;Product name:-Gemigliptintartarate;Inhibitor,DPP,Gemigliptin,Dipeptidyl Peptidase,inhibit;(S)-1-(2-Amino-4-(2,4-bis(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one;1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one
CBNumber:
CB82627898
化学式:
C18H19F8N5O2
分子量:
489.36
MOL File:
911637-19-9.mol

ゲミグリプチン 物理性質

沸点 :
539.1±50.0 °C(Predicted)
比重(密度) :
1.54±0.1 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
DMSO:74.0(Max Conc. mg/mL);151.21(Max Conc. mM)
Ethanol:7.0(Max Conc. mg/mL);14.3(Max Conc. mM)
Water:12.0(Max Conc. mg/mL);24.52(Max Conc. mM)
酸解離定数(Pka):
7.33±0.10(Predicted)

安全性情報

ゲミグリプチン 価格 もっと(1)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01MAS122479
Gemigliptin
911637-19-9 1g ¥1221300 2024-03-01 購入

ゲミグリプチン 化学特性,用途語,生産方法

効能

糖尿病治療薬, DPP-4阻害薬

説明

Gemigliptin is a prolyl-specific dipeptidyl aminopeptidase IV (DPP IV, DPP-4, CD26) inhibitor approved for the treatment of type 2 diabetes mellitus by the Korean Food and Drug Administration in 2012. Gemigliptin was discovered and developed by LG Life Sciences and is now the sixth DPP-4 inhibitor approved for the treatment of type 2 diabetes. At the time this review was prepared, there were no publications describing the discovery strategy and preclinical data that led to the advancement of gemigliptin to the clinic.

使用

Gemigliptin Hydrochloride is used in biological studies as a novel dipeptidyl peptidase IV (DPP-IV) inhibitors and potential antidiabetic drug.

ゲミグリプチン 上流と下流の製品情報

原材料

準備製品


ゲミグリプチン 生産企業

Global( 51)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21691 55
Anqing Chico Pharmaceutical Co., Ltd.
15380796838
chloewu@chicopharm.cn CHINA 341 58
Senova Technology Co. Ltd.
+86-0755-86703119 +8618503098836
info@senovatech.com China 349 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763
sales@tnjchem.com China 25363 58
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
trendseenbio@gmail.com China 11681 58
Aceschem Inc.
+1-817863-6948 +1-(817)863-6948
sales@aceschem.com United States 19639 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33349 58

ゲミグリプチン  スペクトルデータ(1HNMR)


911637-19-9(ゲミグリプチン)キーワード:


  • 911637-19-9
  • GeMigliptin
  • GeMigliptin Tartarate
  • Gemigliptin - G10587
  • (S)-1-(2-Amino-4-(2,4-bis(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one
  • GeMigliptin WS
  • (S)-1-(2-amino-4-(2,4-bis(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one hydrochloride
  • LC15-0444
  • Gemigliptin Hydrochloride
  • Product name:-Gemigliptintartarate
  • 2-Piperidinone, 1-[(2S)-2-amino-4-[5,8-dihydro-2,4-bis(trifluoromethyl)pyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl]-5,5-difluoro-
  • 1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one
  • Inhibitor,DPP,Gemigliptin,Dipeptidyl Peptidase,inhibit
  • ゲミグリプチン
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