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セリチニブ

セリチニブ 化学構造式
1032900-25-6
CAS番号.
1032900-25-6
化学名:
セリチニブ
别名:
セリチニブ;セリチニブ (JAN)
英語化学名:
Ceritinib (LDK378)
英語别名:
LDK37;LDK378;CS-819;Zykadia;Eritinib;ceritinib;LDK378/LDK-378;LDK378 Ceritinib;Ceritinib, >=98%;Eritinib (LDK378)
CBNumber:
CB82652832
化学式:
C28H36ClN5O3S
分子量:
558.13514
MOL File:
1032900-25-6.mol

セリチニブ 物理性質

沸点 :
720.7±70.0 °C(Predicted)
比重(密度) :
1.251±0.06 g/cm3(Predicted)
外見 :
Off-white solid.
酸解離定数(Pka):
10.16±0.10(Predicted)

安全性情報

セリチニブ 価格 もっと(1)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQJ-9413
Ldk378
1032900-25-6 100mg ¥644400 2018-12-26 購入

セリチニブ 化学特性,用途語,生産方法

効能

抗悪性腫瘍薬, 未分化リンパ腫キナーゼ(ALK)阻害薬

商品名

ジカディア (ノバルティスファーマ)

定義

ChEBI: A member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(piperidin-4-yl)-5-methylphenyl and 2-(isopropylsulfonyl)phenyl substituents. Used for the treatment of ALK-positive metastatic non-small cell lung cancer.

適応症

Ceritinib (Zykadia(R), Novartis), approved in 2014, was developed as a second-generation ALK inhibitor for patients with NSCLC who have developed crizotinib resistance. Ceritinib addresses two of the most common ALK mutants that lead to crizotinib resistance, L1196M andG1269A, but is ineffective for G1202R and F1174C variants of ALK.

セリチニブ 上流と下流の製品情報

原材料

準備製品


セリチニブ 生産企業

Global( 268)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Jurong Coupling Biotechnology Co., Ltd.
13656108824
coupling278191416@hotmail.com CHINA 184 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20039 58
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 19929 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21838 58
Nanjing Gold Pharmaceutical Technology Co. Ltd.
025-84209270 15906146951
025-84209270 wgp@nanjing-pharmaceutical.com CHINA 115 55
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1817 55
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0371-55170693
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Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile
+86-571-56059825 fandachem@gmail.com CHINA 3269 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3014 60

1032900-25-6(セリチニブ)キーワード:


  • 1032900-25-6
  • CS-819
  • LDK378
  • LDK378/LDK-378
  • 5-Chloro-N2-[2-isopropoxy-5-Methyl-4-(4-piperidyl)phenyl]-N4-(2-isopropylsulfonylphenyl)pyriMidine-2,4-diaMine
  • 5-chloro-N2-(2-isopropoxy-5-Methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyriMidine-2,4-diaMine
  • 5-Chloro-N4-[2-[(1-Methylethyl)sulfonyl]phenyl]-N2-[5-Methyl-2-(1-Methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyriMidinediaMine
  • ceritinib
  • LDK378 Ceritinib
  • Ceritinib (LDK378)
  • 2,4-Pyrimidinediamine, 5-chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-
  • 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine LDK 378
  • LDK 378 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine
  • Eritinib (LDK378)
  • Ceritinib, >=98%
  • Eritinib
  • 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)p
  • Zykadia
  • LDK37
  • LDK-378; LDK378;CERITINIB
  • セリチニブ
  • セリチニブ (JAN)
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