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セリチニブ

セリチニブ 化学構造式
1032900-25-6
CAS番号.
1032900-25-6
化学名:
セリチニブ
别名:
セリチニブ;セリチニブ (JAN)
英語化学名:
Ceritinib (LDK378)
英語别名:
LDK37;LDK378;Zykadia;Eritinib;ceritinib;LDK378/LDK-378;LDK378 Ceritinib;Ceritinib, >=98%;Eritinib (LDK378);Ceritinib (LDK378)
CBNumber:
CB82652832
化学式:
C28H36ClN5O3S
分子量:
558.13514
MOL File:
1032900-25-6.mol

セリチニブ 物理性質

安全性情報

セリチニブ 価格 もっと(1)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQJ-9413
Ldk378
1032900-25-6 100mg ¥644400 2018-12-26 購入

セリチニブ 化学特性,用途語,生産方法

効能

抗悪性腫瘍薬, 未分化リンパ腫キナーゼ(ALK)阻害薬

商品名

ジカディア (ノバルティスファーマ)

定義

ChEBI: A member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(piperidin-4-yl)-5-methylphenyl and 2-(isopropylsulfonyl)phenyl substituents. Used for the treatment of ALK-positive metastatic non-small cell lung cancer.

適応症

Ceritinib (Zykadia(R), Novartis), approved in 2014, was developed as a second-generation ALK inhibitor for patients with NSCLC who have developed crizotinib resistance. Ceritinib addresses two of the most common ALK mutants that lead to crizotinib resistance, L1196M andG1269A, but is ineffective for G1202R and F1174C variants of ALK.

セリチニブ 上流と下流の製品情報

原材料

準備製品


セリチニブ 生産企業

Global( 228)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Shandonghaohong biotechnology Co.,ltd.
0635-6175299 13961496334
0635-6175299 sale@inyelchem.com CHINA 44 55
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21935 58
Nanjing Gold Pharmaceutical Technology Co. Ltd.
025-84209270 15906146951
025-84209270 wgp@nanjing-pharmaceutical.com CHINA 115 55
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1529 55
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0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2734 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 661 60

1032900-25-6(セリチニブ)キーワード:


  • 1032900-25-6
  • LDK378
  • 5-Chloro-N2-[2-isopropoxy-5-Methyl-4-(4-piperidyl)phenyl]-N4-(2-isopropylsulfonylphenyl)pyriMidine-2,4-diaMine
  • 5-Chloro-N4-[2-[(1-Methylethyl)sulfonyl]phenyl]-N2-[5-Methyl-2-(1-Methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyriMidinediaMine
  • ceritinib
  • 5-chloro-N2-(2-isopropoxy-5-Methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyriMidine-2,4-diaMine
  • LDK378/LDK-378
  • LDK378 Ceritinib
  • Ceritinib (LDK378)
  • 2,4-Pyrimidinediamine, 5-chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-
  • 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine LDK 378
  • LDK 378 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine
  • Eritinib (LDK378)
  • Ceritinib, >=98%
  • Eritinib
  • 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)p
  • Zykadia
  • LDK37
  • セリチニブ
  • セリチニブ (JAN)
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