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L 2-401

化学構造式
883050-24-6
CAS番号.
883050-24-6
化学名:
别名:
英語名:
L 2-401
英語别名:
CS-563;L 2-401;CCG 50014;CCG50014;CCG 50014;CCG-50014 >=98% (HPLC);4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione;4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione;1,2,4-Thiadiazolidine-3,5-dione, 4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-;Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,inhibit,CCG50014,Inhibitor
CBNumber:
CB82657938
化学式:
C16H13FN2O2S
分子量:
316.35
MOL File:
883050-24-6.mol

L 2-401 物理性質

比重(密度) :
1.398±0.06 g/cm3 (20 ºC 760 Torr)
貯蔵温度 :
2-8°C
溶解性:
DMSO：可溶5mg/mL、透明（加温）
外見 :
粉
色:
白からベージュ

安全性情報

WGK Germany  3

L 2-401 価格 もっと(4)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC4567
CCG 50014 		883050-24-6 10mg ￥65000 2023-06-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC4567
CCG 50014 		883050-24-6 50mg ￥277000 2023-06-01 購入
Sigma-Aldrich Japan SML0908 ≥98% (HPLC)
CCG-50014 ≥98% (HPLC)		 883050-24-6 5mg ￥25100 2024-03-01 購入
Sigma-Aldrich Japan SML0908 ≥98% (HPLC)
CCG-50014 ≥98% (HPLC)		 883050-24-6 25mg ￥64100 2024-03-01 購入

L 2-401 化学特性,用途語,生産方法

説明

CCG-50014 is an inhibitor of regulator of G protein signaling 4 (RGS4) (IC50 = 30 nM) and is > 20-fold selective for RGS4 over other RGS proteins. RGS proteins bind to the Gα subunits of activated heterotrimeric G proteins and accelerate the rate of GTP hydrolysis, acting as GTPase-activating proteins. CCG-50014 irreversibly binds and destabilizes RGS4 with no effect on Gα0, while blocking GTPase activity and Gα0-dependent translocation of RGS4 to the membrane.

L 2-401 上流と下流の製品情報

原材料

準備製品

L 2-401 生産企業

Global( 74)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32480 60
Accela ChemBio Inc. 		(+1)-858-699-3322
info@accelachem.com United States 19965 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674;
 laboratory@coreychem.com China 30255 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354
support@targetmol.com United States 19973 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131981 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 18521732826;
 market@aladdin-e.com China 25015 65
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4121 55

  スペクトルデータ(1HNMR)

L 2-401(883050-24-6)1HNMR
  • 883050-24-6
  • 4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione
  • CCG 50014
  • L 2-401
  • 1,2,4-Thiadiazolidine-3,5-dione, 4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-
  • 4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione
  • CCG50014;CCG 50014
  • CS-563
  • CCG-50014 >=98% (HPLC)
  • Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,inhibit,CCG50014,Inhibitor
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