Chinese english Germany Korea

MI-136

化学構造式
1628316-74-4
CAS番号.
1628316-74-4
化学名:
别名:
英語名:
MI-136
英語别名:
MI-136;CS-2162;MI136;MI 136;HY-19319 (MI 136;MI-136;HY-19319 (MI 136; MI136);;5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in;5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile;1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-;PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate
CBNumber:
CB83121119
化学式:
C23H21F3N6S
分子量:
470.51
MOL File:
1628316-74-4.mol

MI-136 物理性質

沸点 :
654.9±55.0 °C(Predicted)
比重(密度) :
1.45±0.1 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 10 mg/ml
外見 :
A crystalline solid
酸解離定数(Pka):
14.20±0.30(Predicted)

安全性情報

MI-136 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

MI-136 化学特性,用途語,生産方法

説明

MI-136 is an inhibitor of the menin-MLL interaction (IC50 = 31 nM; Kd = 23.6 nM). By blocking MLL recruitment predominantly at the level of the menin-MLL interaction, it can inhibit androgen receptor (AR)-mediated transcription. At 40 mg/kg, MI-136 has been shown to block AR signaling, inhibiting the growth of castration-resistant tumors in mice.

MI-136 上流と下流の製品情報

原材料

準備製品

MI-136 生産企業

Global( 62)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32480 60
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6313 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354
support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43348 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203
 info@chemextension.com China 42057 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131981 58
Shanghai Boyle Chemical Co., Ltd.
sales@boylechem.com China 2923 55

1628316-74-4()キーワード:

セフタジジム
  • 1628316-74-4
  • MI-136
  • MI-136;HY-19319 (MI 136; MI136);
  • HY-19319 (MI 136
  • 1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-
  • 5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile
  • 5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in
  • MI136;MI 136
  • CS-2162
  • PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate
Copyright 2017 © ChemicalBook. All rights reserved