キシリジン (混合物) 化学特性,用途語,生産方法
外観
うすい黄赤色～黄色～緑色透明液体
解説
dimethylaniline．C8H11N(121.18)．(CH3)2C6H3NH2．キシレンのアミノ誘導体で，アミノ基と二つのメチル基との相対的な位置によって6種類の異性体がある．いずれも対応するニトロ化合物を還元してつくられ，アニリンに似た性質を示す．3,4-キシリジン以外は無色の液体．
"0.97～0.99．水に難溶，エタノールに可溶．おもに染料中間体として使用される．
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森北出版「化学辞典（第2版）
化学的特性
Liquid. Slightly soluble inwater;
soluble in alcohol and ether. Combustible.
使用
Chiefly in the manufacture of dyes.
定義
A varying mixture of isomers (2,3-; 2,4-; 2,5-; 2,6-).
危険性
Toxic by ingestion, inhalation, and skin
absorption. Liver damage. Methemoglobinemia.
Possible carcinogen.
健康ハザード
Xylidine causes liver damage in
experimental animals and is a mild methemoglobin
former; it caused tumors of the nasal
cavity in rats.
There are six isomeric forms of xylidenes
with the commercial product consisting primarily
of the 2,4- and 2,6-isomers.
安全性プロファイル
Confirmed carcinogen.
Poison by intravenous route. Moderately
toxic by ingestion. This material, which so
closely resembles aniline in the character of
its toxic effects, is actually twice as toxic as
aniline. It can cause injury to the blood and
the liver. It does not necessarily give any
alarm or warning, such as cyanosis,
headache, and duziness, whch characterize
aniline poisoning. Thus, it may be
considered a more insidious poison than aniline, and severe and possibly fatal
intoxication may come about through skin
absorption. Combustible when exposed to
heat or flame. Can react vigorously with
oxidizing materials. To fight fire, use foam,
CO2, dry chemical. When heated to
decomposition it emits toxic fumes of NOx.
See also ANILINE and other xylidme
entries.
職業ばく露
Xylidines are used in dyestuff
manufacture; as intermediates in the manufacture of pesticides,
antioxidants, pharmaceuticals, and other organic com
pounds.
発がん性
The IARC has determined that there is
sufficient evidence for the carcinogenicity of
2,6-xylidine in experimental animals and inadequate
evidence in humans.5 Overall, 2,6-
xylidine is considered possibly carcinogenic to
humans.
In genotoxic assays, 2,6-xylidine induced
sister chromatid exchanges and chromosomal
aberrations in cultured mammalian cells but
did not induce micronuclei in the bone marrow
of mice treated in vivo; conflicting results have
been reported in the Salmonella typhimurium
assay.
輸送方法
UN1711/Xylidines, solid or liquid, Hazard
Class: 6.1; Labels: 6.1-Poisonous materials.
不和合性
Vapor may form explosive mixture with
air. Contact with hypo chlorite salts and bleaches form
explosive chloroamines. Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates,
chlorine, bromine, fluorine, etc.); contact may cause fires
or explosions. Keep away from alkaline materials, strong
bases, strong acids, oxoacids, and epoxides. A chemical
base: Will neutralize acids to form salts plus water with an
exothermic reaction. May be incompatible with isocyanates,
halogenated organics, peroxides, phenols (acidic),
epoxides, anhydrides, and acid halides. Flammable gaseous
hydrogen is generated by amines in combination with
strong reducing agents such as hydrides, nitrides, alkali
metals, and sulfides.
廃棄物の処理
Incineration; oxides of
nitrogen are removed from the effluent gas by scrubber,
catalytic, or thermal device.
キシリジン (混合物) 上流と下流の製品情報
原材料
準備製品