N,N'''-[イミノビス(8,1-オクタンジイル)]ビスグアニジン/酢酸,(1:x) 化学特性,用途語,生産方法
使用
Iminoctadine triacetate is used as a seed treatment or spray for
control of Septoriu nodorum, Tilletia caries, Fusarium spp. and Helminthosporium
spp. in cereals. It is also used on citrus fruit and apples.
代謝経路
Iminoctadine is a strong base with two guanidino groups with pKa >13
and an amino group with pKa >9. It is ionised at all pH values typically
encountered in the environment. Although the tri-cation is highly polar
it will be strongly sorbed to soils by the ion exchange mechanism as well
as by hydrophobic interactions of its alkyl chains. Amino compounds
usually readily form unextractable residues in soils. For these reasons the
fungicide is strongly sorbed to soils and there it has low biological availability
to plants and animals and is protected from microbial degradation.
The only major identified products of transformation were products of
photooxidation and the deamidinated products detected in rats.
Degradation
Iminoctadine triacetate is stable in neutral and aqueous acidic media but
unstable in alkaline conditions. There was no appreciable hydroysis of
iminoctadine in buffer solutions at pH 5,7 and 9 after one month at 25 °C
(PM). [
14C-guanidine]Iminoctadinetr iacetate was coated onto glass plates
and exposed to artificial (12 hours day
-1) or natural sunlight. Loss by
volatilisation was negligible over 336 hours. Photodegradation was initially
rapid (DT
50 40 hours) but subsequently slowed (DT
50 912 hours).
One major and several minor photoproducts were detected after irradiation
for 336 hours and in total represented 69% of the applied radioactivity
of which the major product accounted for 31%. The major
metabolite was converted into pyrimidine derivatives to aid analysis
by IR, NMR and MS methods. The major photoproduct was tentatively
identified as 4- or 6-methyl-5-oxo-9-azaheptadecane-1,17-diguanidine
(2 or 3, Scheme 1) and it was formed by photo-oxidation and methylation
of adjacent methylene groups. One of the intermediates in the formation
of 2 or 3 was another unidentified photo-oxidation product of iminoctadine
(Sato et al., 1985b).
N,N'''-[イミノビス(8,1-オクタンジイル)]ビスグアニジン/酢酸,(1:x) 上流と下流の製品情報
原材料
準備製品