SU5416
SU5416 物理性質
- 融点 :
- 226-228 °C
- 沸点 :
- 481.4±45.0 °C(Predicted)
- 比重(密度) :
- 1.256±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- -20°C
- 溶解性:
- H2O: 不溶
- 酸解離定数(Pka):
- 12.59±0.20(Predicted)
- 外見 :
- 黄橙色の固体
- 色:
- 黄色から黄橙色
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TOC3037 |
SU5416
SU 5416 |
204005-46-9 |
10mg |
¥57000 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TOC3037 |
SU5416
SU 5416 |
204005-46-9 |
50mg |
¥244000 |
2024-03-01 |
購入 |
Sigma-Aldrich Japan
|
S8442 |
≥98% (HPLC)
SU 5416 ≥98% (HPLC) |
204005-46-9 |
5mg |
¥30400 |
2024-03-01 |
購入 |
Sigma-Aldrich Japan
|
S8442 |
≥98% (HPLC)
SU 5416 ≥98% (HPLC) |
204005-46-9 |
25mg |
¥95100 |
2024-03-01 |
購入 |
SU5416 化学特性,用途語,生産方法
使用
SU 5416 is a vascular endothelial growth factor receptor blocker that may induce severe pulmonary hypertension if combined with chronic hypoxia. Angiogenesis inhibitor used for deep penetration into t
umor tissues.
生物活性
Inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET. Displays no activity against EGFR, HER2, IGF1R and PDGFR. Inhibits tumor vascularization and growth of multiple tumor types.
Biochem/physiol Actions
SU 516 inhibits the activity of neuronal nitric oxide synthase and protects the neuronal cells from nitric oxide-mediated neurotoxicity.1 It also acts an agonist of aryl hydrocarbon receptor and is an effective clinical agent for treating autoimmune diseases and transplant rejection.2
SU5416 上流と下流の製品情報
原材料
準備製品
SU5416 生産企業
Global( 157)Suppliers
204005-46-9(SU5416)キーワード:
- 204005-46-9
- H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro-
- SeMaxinib
- SU 5416 (SeMaxinib)
- SU5416 /SU-5416
- (Z)-3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one
- 3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one
- 3-[(3,5-diMethyl-1H-pyrrol-2-yl)Methylidene]-1H-indol-2-one
- SEMAXINIB(SU 5416)
- 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
- VEGFR2 Kinase Inhibitor III
- 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-on
- 17022
- 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one
- (3Z)-3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
- SEMAXINIB; SU-5416; SU 5416
- (E)-3-((3,5-DIMETHYL-1H-PYRROL-2-YL)METHYLENE)INDOLIN-2-ONE
- VEGFR2 Kinase Inhibitor III - CAS 204005-46-9 - Calbiochem
- 5-Dimethyl-1H-pyrrol-2-yl)met
hylene)indolin-2-one
- (Z)-3-((3
- SU5416; SU-5416; SU 5416; SUGEN 5416; SEMOXIND; SEMAXANIB
- Sugen 5416
- SU 5416, 98%, a VEGFR2/Flk1 inhibitor
- SU 5416 semaxanib
- SU54161
- 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
- SU5416