2,3-ジヒドロキシナフタレン 化学特性,用途語,生産方法
外観
白色～うすい褐色, 結晶～結晶性粉末
溶解性
エタノールに溶ける。エタノール、エーテルに易溶。ベンゼン、リグロイン、及び熱水に可溶。
用途
有機合成原料。
化学的特性
Off white to redish white powder. 2,3-Naphthalenediol [92-44-4], mp 161℃, gives a dark blue
color with iron(III) chloride; is aminated to 2-
amino-3-naphthol at 140℃ and 2,3-naphthalenediamine at 240℃; and couples with diazotized anilines in the 1- or 1,4-positions.
使用
2,3-Dihydroxynaphthalene is used in making dyes, pigments, fluorescent whiteners, tanning agents, antioxidants, and antiseptics.
一般的な説明
2,3-Dihydroxynaphthalene is a polyhydroxy phenol. It is an aromatic dihydroxy compound having hydroxyl groups at
ortho positions. Its reaction with molybdenum(VI) complexes has been reported. The asymmetric oxidative coupling polymerization of 2,3-dihydroxynaphthalene using the Cu(I)-bisoxazoline complex as catalyst has been reported to afford poly(2,3-dihydroxy-1,4-naphthylene), having a continuous 1,1′-bi-2-naphthol main chain structure. The nitrodisplacement reaction between nitrophthalodinitriles and 2,3-dihydroxynaphthalene has been investigated.
健康ハザード
2,3-Naphthalenediol shows low toxicity andmild irritant actions on the skin and eyes. Theoral LD50 value for rats of a 5% solutionin propylene glycol may be on the orderof 675 mg/kg (calculated by the method ofWeil). The intravenous LD50 value for miceis 56 mg/kg. At 1% concentration, it causedslight eye irritation in female albino rabbitsand exhibited erythemal response in guineapigs. At the 0.1% level (concentration in hairdye), it had no reaction on human skin. Thiscompound was nonmutagenic in Salmonellatyphimurium strain tests.
There is very little information in the literatureon the toxicity of 2,3-naphthalenediol.Assessment by the CIR expert panel on thesafety of this compound as used in cosmeticshas been inconclusive (Cosmetic, Toiletryand Fragrance Association 1987b).
合成
2,3-Dihydroxynaphthalene is prepared by caustic fusion of 3-hydroxynaphthalene-2,6-disulfonic acid followed by treatment with dilute sulfuric acid under pressure, or by acid desulfonation of 2,3-dihydroxynaphthalene-6-sulfonic acid.
2,3-ジヒドロキシナフタレン 上流と下流の製品情報
原材料
2H-1,3-ナフトジオキソール
(1aS,1bR,2aS,6bR)-1a,1b,2a,6b-テトラヒドロナフト[1,2-b:3,4-b']ビスオキシレン
2,3-ジアセトキシナフタレン
準備製品