抗SUMO-1抗体 ウサギ宿主抗体 化学特性,用途語,生産方法
使用
Anti-SUMO-1 antibody produced in rabbit has been used in immunoblotting assay.
一般的な説明
The SUMO-1 (small ubiquitin-like modifier 1) gene is mapped to human chromosome 2q33.1 and is highly conserved. The protein structure includes an α-helix core surrounded by four-stranded β-sheets.
Biochem/physiol Actions
SUMO (small ubiquitin-like modifier) proteins are associated with a number of cellular processes. SUMOylation mediated by SUMO1 is involved in nuclear transport mechanism, apoptosis, regulation of cyclin-dependent kinase 6 and protein stability. SUMO1 regulates tumor suppressor p53 protein, a transcription factor that is termed as the “guardian of the genome” plays a key role in the cell cycle events. Unlike ubiquitination which directs proteins for degradation, SUMOylation aims to alter the stability, localization and the function of the target protein.
抗SUMO-1抗体 ウサギ宿主抗体 上流と下流の製品情報
原材料
準備製品