バナジノセン ジクロリド 化学特性,用途語,生産方法
外観
緑色～暗緑色、結晶性粉末～粉末
用途
有機合成原料。
使用上の注意
不活性ガス封入
化学的特性
dark green crystalline powder
使用
Vanadocene dichloride is used like other metallocenes as a
catalyst, ultraviolet absorber, reducing agent, free radical
scavenger, antiknock agent in gasoline, and as a developmental
anticancer drug.
一般的な説明
Pale green crystals or green powder.
空気と水の反応
Extremely sensitive to exposure to air. Also extremely sensitive to moisture; decomposes in water
反応プロフィール
Organometallics, such as BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE, are reactive with many other groups. Incompatible with acids and bases. Organometallics are good reducing agents and therefore incompatible with oxidizing agents. Often reactive with water to generate toxic or flammable gases. Organometallics containing halogens (fluorine, chlorine, bromine, iodine) bonded to the metal typically with generate gaseous hydrohalic acids (HF, HCl, HBr, HI) with water.
火災危険
Flash point data for BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE are not available. BIS(CYCLOPENTADIENYL)VANADIUM DICHLORIDE is probably combustible.
応用例（製薬）
Vanadocene dichloride [( η
5-C
5H
5)
2VCl
2, dichloro bis(η
5-cyclopentadienyl)vanadium(IV)] is structurally very similar to Cp
2TiCl
2. It also consists of a metal centre with an oxidation number of +IV, in this case vanadium, and two Cp and two chloride ligands. Vanadocene dichloride is a 17-electron complex containing an unpaired electron and is therefore paramagnetic .
Vanadocene dichloride has found application as a catalyst for polymerisation reactions, but was also intensively studied as an anticancer agent in parallel to Cp
2TiCl
2 because of their structural similarities. Vanadocene dichloride has proven to be even more effective than its titanium analogue as an antiproliferative agent against both animal and human cell lines in preclinical testing. The main problems are the difficult characterisation of the active vanadium compounds and their fast hydrolysis.
バナジノセン ジクロリド 上流と下流の製品情報
原材料
準備製品