GW-4064
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- CAS番号.
- 278779-30-9
- 化学名:
- GW-4064
- 别名:
- GW-4064;3-[2-(2-クロロ-4-{[3-(2,6-ジクロロフェニル)-5-(プロパン-2-イル)-1,2-オキサゾール-4-イル]メトキシ}フェニル)エテニル]安息香酸;3-[2-クロロ-4-[[3-(2,6-ジクロロフェニル)-5-イソプロピルイソオキサゾール-4-イル]メトキシ]スチリル]安息香酸
- 英語名:
- GW 4064
- 英語别名:
- CS-278;GW 4064;GW4064;GW 4064;3-(2,6-Dichlorophenyl)-4-(3'-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole;3-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-isopropyl-4-isoxazolyl]methoxy]styryl]benzoic Acid;3-(2-Chloro-4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid;3-[2-[2-Chloro-4-[3-(2,6-dichlorophenyl)-5-isopropyl-isoxazol-4-ylMethoxy]phenyl]vinyl]benzoic;GW-4064,3-[2-[2-Chloro-4-[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-ylMethoxy]phenyl]vinyl]benzoi;3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]Methoxy]phenyl]vinyl]benzoic acid;3-[2-[2-Chloro-4-[[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-benzoic Acid
- CBNumber:
- CB8799852
- 化学式:
- C28H22Cl3NO4
- 分子量:
- 542.84
- MOL File:
- 278779-30-9.mol
- MSDS File:
- SDS
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GW-4064 物理性質
- 融点 :
- >175°C (dec.)
- 沸点 :
- 702.1±60.0 °C(Predicted)
- 比重(密度) :
- 1.367±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- DMSO：可溶10mg/mL、透明
- 酸解離定数(Pka):
- 4.13±0.10(Predicted)
- 外見 :
- 粉
- 色:
- 白い
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TOC2473 |
GW 4064 |
278779-30-9 |
10mg |
￥56000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TOC2473 |
GW 4064 |
278779-30-9 |
50mg |
￥240000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
G5172 |
≥97% (HPLC)
GW4064 ≥97% (HPLC) |
278779-30-9 |
5mg |
￥35500 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
G5172 |
≥97% (HPLC)
GW4064 ≥97% (HPLC) |
278779-30-9 |
25mg |
￥133000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
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W01TRCG931000 |
GW 4064 |
278779-30-9 |
25mg |
￥119400 |
2024-03-01 |
購入 |
GW-4064 化学特性,用途語,生産方法
一般的な説明
GW4064 is a synthetic isoxazole, which is used to decipher the cellular and physiological functions of farnesoid X receptor (FXR). It is an estrogen receptor-related receptors (ERRs) agonist.
生物活性
Selective, non-steroidal farnesoid X receptor (FXR) agonist (EC 50 = 15 nM). Displays no activity at other nuclear receptors at concentrations up to 1 μ M. Improves hyperglycaemia and hyperlipidaemia in diabetic db/db mice.
GW-4064 上流と下流の製品情報
原材料
準備製品
GW-4064 生産企業
Global( 155)Suppliers
278779-30-9(GW-4064)キーワード:
- 278779-30-9
- GW 4064
- Benzoic acid, 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-GW 4064
- 3-[2-[2-Chloro-4-[[3-(2,6-Dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-benzoic Acid
- 3-(2,6-Dichlorophenyl)-4-(3'-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole
- 3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]Methoxy]phenyl]vinyl]benzoic acid
- Benzoic acid, 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-Methylethyl)-4-isoxazolyl]Methoxy]phenyl]ethenyl]-
- GW-4064,3-[2-[2-Chloro-4-[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-ylMethoxy]phenyl]vinyl]benzoi
- 3-[2-[2-Chloro-4-[3-(2,6-dichlorophenyl)-5-isopropyl-isoxazol-4-ylMethoxy]phenyl]vinyl]benzoic
- 3-(2,6-Dichlorophenyl)-4-(3'-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole GW 4064
- GW 4064,3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoicacid
- CS-278
- GW4064;GW 4064
- 3-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-isopropyl-4-isoxazolyl]methoxy]styryl]benzoic Acid
- 3-(2-Chloro-4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid
- GW-4064
- 3-[2-(2-クロロ-4-{[3-(2,6-ジクロロフェニル)-5-(プロパン-2-イル)-1,2-オキサゾール-4-イル]メトキシ}フェニル)エテニル]安息香酸
- 3-[2-クロロ-4-[[3-(2,6-ジクロロフェニル)-5-イソプロピルイソオキサゾール-4-イル]メトキシ]スチリル]安息香酸