SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

 化学構造式
165377-44-6
CAS番号.
165377-44-6
化学名:
别名:
英語名:
SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE
英語别名:
SA-4503;CS-2246;SA-4503(2HCl);Cutamesine HCl;SA 4503;SA-4503;SA4503 >=98% (HPLC);Cutamesine hydrochloride;AGY94806 dihydrochloride;SA 4503 (dihydrochloride);Cutamesine dihydrochloride
CBNumber:
CB91011619
化学式:
C23H32N2O2.2ClH
分子量:
441.44
MOL File:
165377-44-6.mol

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE 物理性質

融点 :
250-252°C
貯蔵温度 :
2-8°C
溶解性:
DMSO (最大 5mg/ml) または水 (少なくとも 25mg/ml まで) に可溶。
外見 :
色:
白からベージュ
安定性::
-20°C の DMSO または蒸留水で最長 1 か月間保存できます。

安全性情報

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE 価格 もっと(6)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQM-1454
1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride
165377-44-6 250mg ¥130000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQM-1454
1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride
165377-44-6 1g ¥325000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) SML2181 SA4503 ≥98% (HPLC)
≥98% (HPLC)
165377-44-6 5mg ¥15900 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) SML2181 SA4503 ≥98% (HPLC)
≥98% (HPLC)
165377-44-6 25mg ¥64100 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC4951
SA 4503 dihydrochloride
165377-44-6 10mg ¥68000 2024-03-01 購入

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE 化学特性,用途語,生産方法

使用

SA 4503 Dihydrochloride is a novel and selective σ1 receptor agonist.

Biochem/physiol Actions

SA4503 is a high affinity, orally active non-opioid intracellular receptor sigma-1 (σ1R) selective agonist (IC50 = 17.4 nM against 200 nM (+)-pentazocine for binding σ1R), exhibiting ~100-fold less affinity for the sigma 2 receptor subtype (σ2R) and little or no affinity toward 36 other receptors, ion channels and second messenger systems. Oral administration is reported to elicit cerebral acetylcholine (ACh) release in rat frontal cortex and hippocampus (5-20 mg/kg p.o.) and reduce immobility time in a mouse forced swimming test (Immobility time = 214.8 s without vs. 111.6 s with 1.0 mg/kg oral dosage).

SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE 上流と下流の製品情報

原材料

準備製品


SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE 生産企業

Global( 98)Suppliers
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165377-44-6()キーワード:


  • 165377-44-6
  • SA 4503 (dihydrochloride)
  • Cutamesine dihydrochloride
  • 1-[2-(3,4-DiMethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
  • SA-4503
  • SA-4503,1-(3,4-DIMETHOXYPHENETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE
  • 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazinedihydrochloride
  • 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine hydrochloride
  • SA-4503(2HCl)
  • Cutamesine HCl (SA-4503 HCl)
  • Cutamesine HCl
  • Cutamesine hydrochloride
  • SA4503; SA 4503; SA-4503; AGY94806; AGY-94806; AGY 94806; CUTAMESINE HCL; CUTAMESINE HYDROCHLORIDE
  • AGY94806 dihydrochloride
  • SA4503 DIHYDROCHLORIDE;AGY94806 DIHYDROCHLORIDE
  • CS-2246
  • SA 4503;SA-4503
  • SA4503 >=98% (HPLC)
  • 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazin...
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