B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid
B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid 物理性質
- 沸点 :
- 529.2±42.0 °C(Predicted)
- 比重(密度) :
- 1.37±0.1 g/cm3(Predicted)
- 酸解離定数(Pka):
- 8.25±0.30(Predicted)
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
警告 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H227 |
引火性液体 |
引火性液体 |
4 |
警告 |
|
P210, P280, P370+P378, P403+P235,P501 |
| H315 |
皮膚刺激 |
皮膚腐食性/刺激性 |
2 |
警告 |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
強い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
|
P264, P280, P305+P351+P338,P337+P313P |
|
| 注意書き |
| P210 |
熱/火花/裸火/高温のもののような着火源から遠ざ けること。－禁煙。 |
| P264 |
取扱い後は皮膚をよく洗うこと。 |
| P264 |
取扱い後は手や顔をよく洗うこと。 |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
| P302+P352 |
皮膚に付着した場合：多量の水と石鹸で洗うこと。 |
| P305+P351+P338 |
眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
| P337+P313 |
眼の刺激が続く場合：医師の診断/手当てを受けること。 |
| P370+P378 |
火災の場合：消火に．．．を使用すること。 |
|
B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid 化学特性,用途語,生産方法
使用
B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
合成
12.6g of intermediate (A) and 500 mL of tetrahydrofuran (dehydrated) were put in a flask, and the resultant
was cooled to -78??C. 28 mL of n-BuLi (1.60M in hexane) was added, and stirring was conducted for 2 hours while
elevating the temperature to 0??C. Then, the solution was again cooled to -78??C, and 11.6g of B(OMe) 3 was added. After
stirring at 10 minutes at -78??C, stirring was further conducted for 5 hours while gradually elevating the temperature to
room temperature. After completion of the reaction, 1 N HCl aq. (100 mL) was added, and the reaction solution was stirred at room
temperature for 1 hour. Then, the solution was transferred to a separating funnel, and extracted with ethyl acetate. This solution was dried with MgSO 4, concentrated and washed with hexane, whereby 7.2g (yield: 65%) of white
solids of intermediate (B) were obtained.
B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid 上流と下流の製品情報
原材料
準備製品
B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid 生産企業
Global( 53)Suppliers
- 1627917-17-2
- B-benzo[b]naphtha[2,3-d]furan-2-yl-boronic acid
- Benzo[b]naphtho[2,3-d]furan-2-ylboronic acid
- Boronic acid,B-benzo[b]naphtho[2,3-d]furan-2-yl-
- naphtho[2,3-b]benzofuran-2-ylboronic acid
- naphtho[2,3-b][1]benzofuran-2-ylboronic acid
- NDPBA
- B-benzo[b]naphtho[2,3-d]furan-2-yl-boronic acid
- CUSTOMS SYNTHESIS
- Benzo [B] naphthol [2, 3-d] furan-2-boric acid