クロロメチルジメチルフェニルシラン
クロロメチルジメチルフェニルシラン 価格
もっと(9)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-4480 |
クロロメチルジメチルフェニルシラン
Chloromethyldimethylphenylsilane |
1833-51-8 |
5g |
￥18000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-4480 |
クロロメチルジメチルフェニルシラン
Chloromethyldimethylphenylsilane |
1833-51-8 |
25g |
￥72500 |
2024-03-01 |
購入 |
|
東京化成工業
|
C1419 |
クロロメチルジメチルフェニルシラン >97.0%(GC)
Chloromethyldimethylphenylsilane
>97.0%(GC) |
1833-51-8 |
5g |
￥8700 |
2024-03-01 |
購入 |
|
東京化成工業
|
C1419 |
クロロメチルジメチルフェニルシラン >97.0%(GC)
Chloromethyldimethylphenylsilane
>97.0%(GC) |
1833-51-8 |
25g |
￥25400 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
347094 |
(クロロメチル)ジメチルフェニルシラン 98%
(Chloromethyl)dimethylphenylsilane 98% |
1833-51-8 |
10g |
￥13000 |
2024-03-01 |
購入 |
クロロメチルジメチルフェニルシラン 化学特性,用途語,生産方法
外観
無色～ほとんど無色透明液体
物理的性質
bp 106–107°C/15 mmHg; d 1.024 g cm?3
使用
The first reported preparation and use of
(chloromethyl)dimethylphenylsilane was in 1949.At the time,
the main utility of (chloromethyl)dimethylphenylsilane was as
the starting material for conversion to the corresponding Grignard
reagent (see below). Since then, it has also been used for heteroatom
alkylation, carbon alkylation, and conversion to a variety
of organometallic and organolanthanide reagents. The main advantage
of this reagent over the closely related (chloromethyl)trimethylsilane
is the ability of (chloromethyl)dimethylphenylsilane
to undergo a Fleming oxidation, thus allowing (chloromethyl)dimethylphenylsilane
to serve as a masked hydroxyl group. This
utility has been exploited for both the C-substituted and Nsubstituted
adducts. A major disadvantage of the use of
(chloromethyl)dimethylphenylsilane is its propensity to undergo
rearrangements under a variety of conditions (see below). (Chloromethyl)
dimethylphenylsilane is used as the precursor for the
preparation of (phenyldimethylsilyl)methoxymethyl chloride
(SMOM-Cl), a hydroxyl protecting group.
(Chloromethyl)dimethylphenylsilane (1) can
be utilized to install a silylmethyl group on carbon via base promoted
C-alkylation of terminal alkynes,dihydropyrazines,malonic
esters,phenylacetonitriles,sulfoxides,and imines.Although
has been used directly in the alkylation, conversion to
the corresponding iodide via Finkelstein displacement (eq 1)
prior to alkylation is sometimeswarranted. Except for the malonic
esters (eq 2), strongly basic conditions and lowtemperatures (with
slow warming) are generally employed in the transformation (eqs
3 and 4).
製造方法
can be prepared either by the reaction
of phenylmagnesium bromide with chloro(chloromethyl)dimethylsilane
in ether at reflux,or by the reaction of phenylmagnesium
bromide with chloro(chloromethyl)dimethylsilane
in the presence of catalytic (N,N,N,N-tetramethylethylenediamine)
zinc in 1,4-dioxane at 20°C.
クロロメチルジメチルフェニルシラン 上流と下流の製品情報
原材料
準備製品
クロロメチルジメチルフェニルシラン 生産企業
Global( 124)Suppliers
クロロメチルジメチルフェニルシラン スペクトルデータ(1HNMR、13CNMR、IR1、MS)
1833-51-8(クロロメチルジメチルフェニルシラン)キーワード:
- 1833-51-8
- (chloromethyl)dimethylphenyl-silan
- Dichloromethyldimethylphenylsilane
- Phenyldimethyl(chloromethyl)silane
- CHLOROMETHYLDIMETHYLPHENYLSILANE
- Silane, (chloromethyl)dimethylphenyl-
- Dimethylphenylsilyldichloromethane
- Chloromethylphenyldimethylsilane
- Phenyl(chloromethyl)dimethylsilane
- dimethyl(phenyl)
- Chloromethyldimethylphenylsilane >
- Benzene, [(chloromethyl)dimethylsilyl]-
- DK635
- DK180
- クロロメチルジメチルフェニルシラン
- ジメチルフェニルシリルジクロロメタン
- クロロメチルフェニルジメチルシラン
- (ジクロロメチル)ジメチルフェニルシラン
- (クロロメチル)ジメチルフェニルシラン
- (クロロメチル)ジメチル(フェニル)シラン
- フェニル(クロロメチル)ジメチルシラン
- ケイ素化合物
- ケイ素化合物 (合成用)
- 構造分類
- 有機合成化学
- Si-(C)4化合物