C6セラミド
C6セラミド 物理性質
- 融点 :
- 76-77°C
- 沸点 :
- 521.03°C (rough estimate)
- 比重(密度) :
- 1.0077 (rough estimate)
- 屈折率 :
- 1.6000 (estimate)
- 貯蔵温度 :
- -20°C
- 溶解性:
- 100% エタノールに 25mg/ml、DMSO に 50mg/ml で可溶。
- 酸解離定数(Pka):
- 13.53±0.20(Predicted)
- 外見 :
- 粉
- 色:
- 白い
- 安定性：:
- 冷凍庫 -20℃
- LogP:
- 7.463 (est)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01CAY62525 |
C6 Ceramide (d18:1/6:0) |
124753-97-5 |
1mg |
￥5000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01CAY62525 |
C6 Ceramide (d18:1/6:0) |
124753-97-5 |
5mg |
￥20400 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
860506P |
N-hexanoyl-D-erythro-sphingosine, powder
C6 Ceramide (d18:1/6:0) N-hexanoyl-D-erythro-sphingosine, powder |
124753-97-5 |
5mg |
￥25700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
860506P |
N-hexanoyl-D-erythro-sphingosine, powder
C6 Ceramide (d18:1/6:0) N-hexanoyl-D-erythro-sphingosine, powder |
124753-97-5 |
10mg |
￥44200 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCC262600 |
C6セラミド
C6 Ceramide |
124753-97-5 |
5mg |
￥29400 |
2024-03-01 |
購入 |
C6セラミド 化学特性,用途語,生産方法
説明
C6 ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides. C6 ceramide mediates many diverse biological activities including apoptosis, activation of protein phosphatase 2A, and inhibition of the mitochondrial respiratory chain. It also enhances the expression of COX-2 in rat granulosa cells and stimulates the growth of bovine aortic smooth muscle cells. C6 ceramide acts in neuronal axons to inhibit neurite growth.
化学的特性
Off White Powder
使用
C6 Ceramide (d18:1/6:0) has been used as a chemotherapeutic agent to test its anti-tumor effect in breast cancer cells and ovarian cancer cell lines. It has also been used to test chemo-sensitization effects in cancer cells.
一般的な説明
Biologically active, cell-permeable, non-physiological ceramide analog. Induces a dramatic arrest in the G
0/G
1 phase of the cell cycle. Activates MAP kinase. Activates protein phosphatase 2A (PP2A) at 10 nM. Inhibits diacylglycerol accumulation and phospholipase D (PLD) activation in fibroblasts. Induces apoptosis in MOLT-4 leukemia cells.
C6セラミド 上流と下流の製品情報
原材料
準備製品
C6セラミド 生産企業
Global( 89)Suppliers
124753-97-5(C6セラミド)キーワード:
- 124753-97-5
- N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecen-1-yl]hexanaMide
- C6 Ceramide (d18:1/6:0)
- N-HEXANOYL-D-ERYTHRO-SPHINGOSINE;C6 CERAMIDE (D18:1/6:0)
- 6-Hexanoyl-D-erythro-sphingosine, 99+%
- C6 ceramide, Caproyl ceramide, N-Caproyl-D-sphingosine
- 6-HEXANOYL-D-ERYTHRO-SPHINGOSINE, SYNTHETICAL, 99+%
- 6-Hexanoyl-D-erythro-sphingosine, synthetical
- 6-Hexanoyl-D-erythro-sphingosine,99+%,synthetical
- 6-Hexanoyl-D-erythro-sphingosineCeramide C6
- CAPROYL CERAMIDE
- C6 CERAMIDE OF D-ERYTHRO-C8-SPHINGOSINE
- C6 CERAMIDE
- C6-D-ERYTHRO-CERAMIDE
- C8 SPHINGOID BASE
- D-ERYTHRO-SPHINGOSINE, N-HEXANOYL-
- 06:0 CERAMIDE
- 6-HEXANOYL-D-ERYTHRO-SPHINGOSINE
- N-CAPROYL-C18-SPHINGOSINE
- N-CAPROYL-D-SPHINGOSINE
- N-HEXANOYL-D-ERYTHRO-SPHINGOSINE
- N-HEXANOY-D-SPHINGOSINE
- N-HEXANOYLSPHINGOSINE
- N-HEXANOYLSPHINGOSINE, D-ERYTHRO
- N-HEXANOYL-D-SPHINGOSINE
- N-HEXANOYL-D-SPHINGOSINE FROM SYNTHETIC D-SPHINGOSINE
- CERAMIDE C6
- alpha-Hydroxyoctadecanoyl-phytosphingosine
- D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem
- Hexanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
- C6セラミド
- N-ヘキサノイル-D-スフィンゴシン
- N-[(2S,3R,4E)-1,3-ジヒドロキシオクタデカ-4-エン-2-イル]ヘキサンアミド
- N-ヘキサノイルスフィンゴシン
- (2S,3R,E)-2-(ヘキサノイルアミノ)-4-オクタデセン-1,3-ジオール
- D-erythro-デヒドロ-C6-セラミド
- D-C6セラミド
- N-ヘキサノイル-D-erythro-スフィンゴシン
- N-[(1S,2R,3E)-1-(ヒドロキシメチル)-2-ヒドロキシ-3-ヘプタデセニル]ヘキサンアミド