ChemicalBook
Chinese english Germany Korea

1,4-フェニレンジアミン

1,4-フェニレンジアミン 化学構造式
106-50-3
CAS番号.
106-50-3
化学名:
1,4-フェニレンジアミン
别名:
1,4-フェニレンジアミン;1,4-ベンゼンジアミン;p-フェニレンジアミン;1,4-フェニレンビスアミン;1,4-フェニルジアミン;1,4-ジアミノベンゼン;C.I.デベロッパー13;ウルソールD;4-アミノアニリン;ベンゼン-1,4-ジアミン;C.I.オキシデーションベース10;pフェニレンジアミン;パラフェニレンジアミン;1,4‐フェニレンジアミン標準品;P‐フェニレンジアミン;P-フェニレンジアミン (PPD)PPD;P-フェニレンジアミン STANDARD;1 , 4 - フェニレンジアミン;p-フェニレンジアミン Standard, 2.0 mg/mL in MeOH;p-フェニレンジアミン (PPD)PPD, 100 µg/mL in MeOH
英語化学名:
p-Phenylenediamine
英語别名:
nakoh;furrod;Nako H;rodold;ursold;Furro D;peltold;renalpf;Rodol D;Ursol D
CBNumber:
CB9852680
化学式:
C6H8N2
分子量:
108.14
MOL File:
106-50-3.mol

1,4-フェニレンジアミン 物理性質

融点 :
139 °C
沸点 :
267 °C(lit.)
比重(密度) :
1.135 g/cm3 (20℃)
蒸気密度:
3.7 (vs air)
蒸気圧:
1.08 mm Hg ( 100 °C)
屈折率 :
1.6339 (estimate)
闪点 :
156 °C
貯蔵温度 :
2-8°C
溶解性:
Soluble in alcohol, chloroform, ether and hot benzene.
外見 :
Powder or Flakes
カラーインデックス :
76060
酸解離定数(Pka):
4.17(at 25℃)
色:
White, gray, or purple to brown
酸塩基指示薬変色域(pH):
NonQ uorescence (3.1) to orange/yellow Q uorescence (4.4)
PH:
9 (50g/l, H2O, 20℃)
水溶解度 :
47 g/L (25 ºC)
Merck :
14,7285
BRN :
742029
暴露限界値:
TLV-TWA 0.1 mg/m3 (ACGIH 1989); TWA skin 0.1 mg/m3 (MSHA and OSHA); IDLH 25 mg/m3 (NIOSH); carcinogenicity: Animal Inadequate Evidence (IARC). .
安定性::
Stable, but oxidizes when exposed to air. Incompatible with oxidizing agents. Store under inert atmosphere.
主な用途:
Nanoparticles, liquid crystal displays, chemical mechanical polishing, bottom antireflective coatings, electrochromic materials, inks, rubber, hair dyes, cosmetics, treatment of virus skin infection
InChIKey:
CBCKQZAAMUWICA-UHFFFAOYSA-N
CAS データベース:
106-50-3(CAS DataBase Reference)
NISTの化学物質情報:
1,4-Benzenediamine(106-50-3)
EPAの化学物質情報:
p-Phenylenediamine (106-50-3)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  T,N,T+,Xn
Rフレーズ  23/24/25-36-43-50/53-63-36/37/38-45-40-48/22-67-52/53
Sフレーズ  28-36/37-45-60-61-28A-24/25-23-53-26
RIDADR  UN 1673 6.1/PG 3
WGK Germany  3
RTECS 番号 SS8050000
8-10-23
自然発火温度 567 °C
TSCA  Yes
国連危険物分類  6.1
容器等級  III
HSコード  29215119
有毒物質データの 106-50-3(Hazardous Substances Data)
毒性 LD50 in rats (mg/kg): 80 orally, 37 i.p. (Burnett)
化審法 (3)-185, (5)-4998
安衛法 変異原性物質
PRTR法 第一種指定化学物質
毒劇物取締法 劇物
絵表示(GHS)
注意喚起語 Danger
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H301 飲み込むと有毒 急性毒性、経口 3 危険 P264, P270, P301+P310, P321, P330,P405, P501
H311 皮膚に接触すると有毒 急性毒性、経皮 3 危険 P280, P302+P352, P312, P322, P361,P363, P405, P501
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 P264, P280, P302+P352, P321,P332+P313, P362
H317 アレルギー性皮膚反応を起こすおそれ 感作性、皮膚 1 警告 P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 P264, P280, P305+P351+P338,P337+P313P
H331 吸入すると有毒 急性毒性、吸入 3 危険 P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H335 呼吸器への刺激のおそれ 特定標的臓器毒性、単回暴露; 気道刺激性 3 警告
H336 眠気やめまいのおそれ 特定標的臓器毒性、単回暴露; 麻酔作用 3 警告 P261, P271, P304+P340, P312,P403+P233, P405, P501
H351 発がんのおそれの疑い 発がん性 2 警告 P201, P202, P281, P308+P313, P405,P501
H370 臓器の障害 特定標的臓器有害性、単回暴露 1 危険 P260, P264, P270, P307+P311, P321,P405, P501
H373 長期にわたる、または反復暴露により臓器の障 害のおそれ 特定標的臓器有害性、単回暴露 2 警告 P260, P314, P501
H400 水生生物に強い毒性 水生環境有害性、急性毒性 1 警告 P273, P391, P501
H410 長期的影響により水生生物に非常に強い毒性 水生環境有害性、慢性毒性 1 警告 P273, P391, P501
H412 長期的影響により水生生物に有害 水生環境有害性、慢性毒性 3 P273, P501
注意書き
P260 粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。
P261 粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P273 環境への放出を避けること。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P301+P310 飲み込んだ場合:直ちに医師に連絡すること。
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。
P311 医師に連絡すること。
P337+P313 眼の刺激が続く場合:医師の診断/手当てを受けること。
P405 施錠して保管すること。

1,4-フェニレンジアミン 価格 もっと(29)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01ACSALR-147N
para-Phenylenediamine (PPD)
106-50-3 100mg ¥3700 2018-12-26 購入
富士フイルム和光純薬株式会社(wako) W01ACSALR-147S p-フェニレンジアミン (PPD)PPD
p-Phenylenediamine (PPD), 100 ug/mL in MeOH
106-50-3 1mL ¥3700 2018-12-26 購入
東京化成工業 P0170 1,4-フェニレンジアミン >98.0%(GC)(T)
1,4-Phenylenediamine >98.0%(GC)(T)
106-50-3 25g ¥2200 2018-12-04 購入
東京化成工業 P0170 1,4-フェニレンジアミン >98.0%(GC)(T)
1,4-Phenylenediamine >98.0%(GC)(T)
106-50-3 250g ¥7000 2018-12-04 購入
関東化学株式会社(KANTO) 13057-2A p‐フェニレンジアミン >99.0%
p‐Phenylenediamine >99.0%
106-50-3 5g ¥7800 2018-12-13 購入

1,4-フェニレンジアミン MSDS


C.I. 76060

1,4-フェニレンジアミン 化学特性,用途語,生産方法

外観

白色~わずかにうすい紫色, 塊

溶解性

水に可溶, エタノールに易溶, エーテルに可溶。エタノール及びアセトンに溶けやすく、冷水にわずかに溶ける。

用途

1,4-フェニレンジアミン主にエンジニアリングプラスチックの原料として用いられるほか、染髪にも利用される。毒物及び劇物取締法により劇物に指定されている。

用途

アゾ染料、白髪染、ゴム加硫促進剤

使用上の注意

不活性ガス封入

化学的特性

p-Phenylenediamines are white to slightly red crystalline solids. They have been described as gray “light brown” which may result from exposure to air.

物理的性質

White, red, or brown crystals. May darken on exposure to air.

使用

p-Phenylenediamine is used for dyeing hairand fur, in the manufacture of azo dyes, inaccelerating vulcanization of rubber, and inantioxidants.

使用

A hair dye component, paraphenylenediamine, as a contact allergen for treatment of inflammatory diseases.

定義

ChEBI: A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.

一般的な説明

A white to purple crystalline solid (melting point 234 F) that turns purple to black in air. Flash point 309 F. Toxic by skin absorption, inhalation or ingestion. Used for production of aramid fiber, antioxidants, as a laboratory reagent, in photographic developing, and as a dye for hair and furs.

空気と水の反応

Oxidizes on exposure to air. The finely powdered base if suspended in air poses a significant dust explosion hazard. Soluble in water. Even as a solid will spot downwind areas purple/black (Roger Patrick, DuPont Engineer).

反応プロフィール

p-Phenylenediamine is the stongest of the weak aromatic bases. p-Phenylenediamine neutralizes acids in weak exothermic reactions to form salts. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Reacts readily with oxidizing agents .

健康ハザード

p-Phenylenediamine is a moderate to highlytoxic compound; the acute, subacute andchronic toxicity of this amine is greater thanthat of its ortho- and meta-isomers. The acutepoisoning effects in animals were manifestedby lacrimation, salivation, ataxia, tremor,lowering of body temperature, increasedpulse rate, and respiratory depression. Anintraperitoneal dose of 10.8 mg/kg (sus pended in propylene glycol) in male ratscaused the formation of methemoglobin tothe extent of 12.9% after 5 hours (Watan abe et al. 1976). The hydrochloride of thisamine has been reported to cause edemaof the head and neck in animals dosedwith 120–350 mg/kg. p-Phenylenediamine in hair dye formulations produced skinirritation and mild conjunctivial inflamma tion in a variety of test animals (Lloydet al. 1977). In guinea pigs, contact pro duced skin sensitization. Hair dyes con taining p-phenylenediamine damaged visionwhen applied into eyes. In addition, allergicasthma and inflammation of the respiratorytract resulted from exposure to higher con centrations. Reports in early literature citeseveral cases of human poisoning resultingfrom the use of hair dyes containingp-phenylenediamine. The toxic symptomsreported were liver and spleen enlargement,vertigo, gastritis, jaundice, atrophy of liver,allergic asthma, dermatitis, cornea ulcer,burning and redness in eyes, and presbyopia(the latter effects arising from using hair dyeson the eyebrows and eye lashes).
Tests for mutagenicity in Salmonellamicrosome assays (in vitro) were negative.With metabolic activation, upon oxidationwith hydrogen peroxide, most mutagenictests showed positive results. Tests forcarcinogenicity were negative, although itslightly increased the overall tumor ratein experimental animals. After oxidationwith hydrogen peroxide, the amine producedtumors in the mammary glands of female rats(Rojanapo et al. 1986).

火災危険

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

接触アレルゲン

PPD is a colorless compound oxidized by hydrogen peroxide in the presence of ammonia. It is then polymerized to a color by a coupling agent. Although a wellknown allergen in hair dyes, PPD can be found as a cause of contact dermatitis in chin rest stains or in milk testers. It is also a marker of group sensitivity to para amino compounds such as benzocaine, some azo dyes, and some previous antibacterial sulphonamides.

安全性プロファイル

Suspected carcinogen with experimental tumorigenic data. Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Mildly toxic by skin contact. A human skin irritant. Mutation data reported. Implicated in aplastic anemia, Can cause fatal liver damage. The p-form is more toxic and a stronger irritant than the 0and misomers. Wen used as a hair dye it caused vertigo, anemia, gastritis, exfoliative dermatitis, and death. Has caused asthma and other respiratory symptoms in the fur-dyeing industry. Combustible when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use water, Con, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also other phenylenediamine entries and AMINES

職業ばく露

p-Phenylenediamine has been used in dyestuff manufacture, in hair dyes; in photographic developers; in synthetic fibers; polyurethanes, and as a monomer and in the manufacture of improved tire cords. Also used as a gasoline additive and in making antioxidants.

Carcinogenicity

A number of dermal carcinogenesis bioassays have been reported using p-PDA alone in an organic solvent or in combination with hydrogen peroxide. An 85-week study in which female Swiss mice were treated with 5% or 10% p-PDAin acetone, 0.02 mL/animal applied topically, showed no evidence of carcinogenicity.
p-PDA was not found to be carcinogenic when administered by diet to male and female F344 rats and B6C3F1 mice at the dietary doses of 625 or 1250 ppm; the high dose approximated the maximum tolerated dose. An IARC Working Group concluded that on the basis of lack of human data, and inadequate animal data, p-PDA was not classifiable as to its carcinogenicity to humans. A recent meta-analysis of 11 case-control studies and one cohort study of the relationship between p-PDA exposure through use of personal hair dye and bladder cancer did not indicate any causal association.

Source

Bulk quantitities may contain m- and o-phenylenediamine and aniline as impurities.

環境運命予測

Biological. In activated sludge, 3.8% mineralized to carbon dioxide after 5 d (Freitag et al., 1985). In activated sludge inoculum, following a 20-d adaptation period, 80.0% COD removal was achieved (Pitter, 1976).
Photolytic. A carbon dioxide yield of 53.7% was achieved when phenylenediamine (presumably an isomeric mixture) adsorbed on silica gel was irradiated with light (λ >290 nm) for 17 h (Freitag et al., 1985).
Chemical/Physical. p-Phenylenediamine will not hydrolyze because it does not contain a hydrolyzable functional group (Kollig, 1993).

輸送方法

UN1673 Phenylenediamines (o-, m-, p-), Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

純化方法

Crystallise the diamine from EtOH or *benzene, and sublime it in vacuo; protect it from light. The acetate has m 304o. [Beilstein 13 IV 104.]

不和合性

Dust may form explosive mixture with air. A strong reducing agent. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid chlorides; acid anhydrides; chloroformates, and strong bases. Incompatible with organic anhydrides; isocyanates, aldehydes. Heat and light contribute to instability. Keep away from metals.

廃棄物の処理

Controlled incineration whereby oxides of nitrogen are removed from the effluent gas by scrubber, catalytic or thermal device.

1,4-フェニレンジアミン 上流と下流の製品情報

原材料

準備製品


1,4-フェニレンジアミン 生産企業

Global( 383)Suppliers
名前 電話番号 ファックス番号 電子メール 国籍 製品カタログ 優位度
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1870 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21686 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29996 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23981 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8815 58

106-50-3(1,4-フェニレンジアミン)キーワード:


  • 106-50-3
  • 106--50-3
  • P-Phenylenediamine(P.P.D.)WHITE
  • cioxidationbase10
  • Developer 13
  • Developer PF
  • developer13
  • developerpf
  • Durafur Black R
  • durafurblackr
  • Fenylenodwuamina
  • fenylenodwuamina(polish)
  • Fouramine D
  • fouramined
  • Fourrine 1
  • Fourrine D
  • fourrine1
  • fourrined
  • Fur Black 41867
  • Fur Brown 41866
  • Fur Yellow
  • furblack41867
  • furbrown41866
  • Furro D
  • furrod
  • furyellow
  • Futramine D
  • futramined
  • Nako H
  • nakoh
  • Oxidation base 10
  • oxidationbase10
  • 1,4-フェニレンジアミン
  • 1,4-ベンゼンジアミン
  • p-フェニレンジアミン
  • 1,4-フェニレンビスアミン
  • 1,4-フェニルジアミン
  • 1,4-ジアミノベンゼン
  • C.I.デベロッパー13
  • ウルソールD
  • 4-アミノアニリン
  • ベンゼン-1,4-ジアミン
  • C.I.オキシデーションベース10
  • pフェニレンジアミン
  • パラフェニレンジアミン
  • 1,4‐フェニレンジアミン標準品
  • P‐フェニレンジアミン
  • P-フェニレンジアミン (PPD)PPD
  • P-フェニレンジアミン STANDARD
  • 1 , 4 - フェニレンジアミン
  • p-フェニレンジアミン Standard, 2.0 mg/mL in MeOH
  • p-フェニレンジアミン (PPD)PPD, 100 µg/mL in MeOH
  • p-フェニレンジアミン Standard, 1000 µg/mL in Acetonitrile
  • p-フェニレンジアミン, 100 µg/mL in MeOH
  • フルオレン他 (高性能ポリマー研究用試薬)
  • 高性能ポリマー研究用試薬
  • 機能性材料
Copyright 2017 © ChemicalBook. All rights reserved