キチン 化学特性,用途語,生産方法
外観
白色~わずかにうすい褐色, 結晶性粉末~粉末
定義
本品は、海産の無脊椎動物の外骨格から得た多糖類である。主としてN-アセチルーD-グルコサミン基を含む。
溶解性
水,アルコール、エーテルに不溶。濃塩酸、濃硫酸、ジメチルアセトアミド-塩化リチウムに可溶。水、エタノール及びアセトンにほとんど溶けない。
解説
キチン,白色の無定形物質.平均重合度850.[α]D"-14→+56°(濃塩酸,加水分解で変化).水,希アルカリに不溶.濃アルカリと加熱すると脱N-アセチルと分解が起こり,キトサンになる.濃厚無機酸,無水ギ酸などにつけておくと可溶化し,その際,部分分解する.キチナーゼで分解し,N-アセチルグルコサミンを生成する.
森北出版「化学辞典(第2版)
用途
酵素・抗体の固定化担体、抗腫瘍活性剤、抗血栓性膜の調製。
用途
各種凝集剤
製法
キチン,キチンは節足動物,環形動物,軟体動物にキチン-タンパク質複合体として多く分布し,腔腸動物や線虫類にも見いだされ,それらの骨格構造の形成に関与している.とくに節足動物では,蛛(ちゅう)形類,甲殻類,昆虫類などのほとんどすべてに存在する.その表皮は,キチン25~50%(乾燥質量として)とタンパク質,炭酸カルシウムとからなる.通常,カニあるいはエビの甲羅を粉末とし,希塩酸で炭酸カルシウムを除き,アルカリ濃溶液で短時間処理してタンパク質,そのほかのきょう雑物を除いて,水洗してつくる.
化粧品の成分用途
研磨.スクラブ剤、増量剤
毒性
LD50 50 mg/kg(ラット,静脈).
説明
Chitin is the most abundant natural amino polysaccharide. It has a similar annual yield as cellulose. Chitin is a kind of highly valuable material in biomedical applications because of its high biocompatibility, biodegradability and non-toxicity as well as its antimicrobial activity and low immunogenicity. It can be easily processed into gels, membrane, nanofibers, beads, nanoparticle, scaffold and sponges, enables its wide applications. In the tissue engineering, it can be used for manufacturing polymer scaffold to satisfy the demands of repairing, replacing, maintaining, or enhancing the function of a particular tissue or organ. In wound dressing, chitin can be used as antimicrobial reagent. In the field of drug delivery, the water-soluble carboxymethyl chitin (CMC) nanoparticle can be used as an effective carrier in drug delivery.
化学的特性
Chitin is a colorless, crystalline or amorphous powder that is insoluble in water, organic solvents, dilute acids, and alkalis. It dissolves in concentrated mineral acids with simultaneous degradation of the polymer. Although chitosan is insoluble in water, it does dissolve in aqueous organic acids, for example, acetic and formic acids, as well as inorganic acids. Chitin and chitosan preparation can vary due to the source, with compositional differences. Similarly, the physicochemical characteristics of chitin and chitosan differ between crustacean species and preparation methods. Several studies have clearly demonstrated the specific characteristics of these products. The Mw and degree of deacetylation (DD) vary with process conditions. The physicochemical characteristics of chitin and chitosan influence their functional properties. Mw and DD vary with process conditions or different extraction methods. Chitosan's application depends on physical, biological, and chemical properties and chitosan depends on two parameters, such as DD and Mw.
使用
chitin (chitine) is a moisture retainer and film-forming agent. This is a naturally occurring polysaccharide found in the shells of crustaceans, such as shrimp and crab, as well as in some fungi and algae. It is also a naturally occuring fibre found in the shells of shellfish. Used for the analysis of chitinase. lysozyme substrate.
定義
ChEBI: Chitin is a polysaccharide comprisingchains of N-acetyl-d-glucosamine,a derivative of glucose. Chitin isstructurally very similar to celluloseand serves to strengthen the supportingstructures of various invertebrates. It is the second most abundant biopolymer on earth, found especially in insects and fungi.
农业用途
Chitin is a polysaccharidec omprising chains of N-acetyl- D-glucosamine, a derivative of glucose, linked byβ-1,4 bonds and containing about 77 nitrogen atoms. It may be visualized as cellulose in which the hydroxyl groups on the second carbon are replaced by -NHCOCH
3 groups Chitin is structurally very similar to cellulose and serves to strengthen various invertebrates. It offers resistance to chemicals and is present in the cell wall of some fungi as well as in the exoskeleton of insects.
参考文献
Kumar, Majeti NV Ravi. "A review of chitin and chitosan applications." Reactive and functional polymers 46.1 (2000): 1-27.
Jayakumar, R., et al. "Biomedical applications of chitin and chitosan based nanomaterials—A short review." Carbohydrate Polymers 82.2 (2010): 227-232.
キチン 上流と下流の製品情報
原材料
準備製品