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キナゴリド

キナゴリド 化学構造式
94424-50-7
CAS番号.
94424-50-7
化学名:
キナゴリド
别名:
キナゴリド塩酸塩
英語名:
Quinagolide hydrochloride
英語别名:
SDZ 205-502;CV205-502 hydrochloride;Norprolac Hydrochloride;QUINAGOLIDE HYDROCHLORIDE;Quinagolide hydrochloride (CV205-502 hydrochloride);(3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride;rel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride;(3α,4aα,10aβ)-N,N-Diethyl-N'- (1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride;(+/-)-N,N-diethyl-N'-<(3α,4aα,10aβ)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzoquinolinyl>sulfamide hydrochloride
CBNumber:
CB9995839
化学式:
C20H34ClN3O3S
分子量:
432.02
MOL File:
94424-50-7.mol

キナゴリド 物理性質

融点 :
234-236°
貯蔵温度 :
Store at -20°C
溶解性:
DMSO : ≥ 43 mg/mL (99.53 mM)
CAS データベース:
94424-50-7(CAS DataBase Reference)

安全性情報

キナゴリド 価格 もっと(3)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TRCQ580500 キナゴリド塩酸塩
Quinagolide Hydrochloride 		94424-50-7 10mg ￥2604300 2023-06-01 購入
富士フイルム和光純薬株式会社(wako) W01TRCQ580500 キナゴリド塩酸塩
Quinagolide Hydrochloride 		94424-50-7 25mg ￥3793600 2023-06-01 購入
富士フイルム和光純薬株式会社(wako) W01TRCQ580500 キナゴリド塩酸塩
Quinagolide Hydrochloride 		94424-50-7 50mg ￥7980000 2024-03-01 購入

キナゴリド 化学特性,用途語,生産方法

効能

高プロラクチン血症治療薬, ドパミンD2受容体作動薬

説明

Quinagolide is a potent and specific non-ergot dopamine D2 agonist launched in the Netherlands for the treatment of hyperprolactinemia. Quinagolide is effective in inhibiting prolactin secretion by human pituitary tumor and hyperprolactinemia in vitro and in viva A daily dose of as low as 60 pg is able to achieve a pronounced and prolonged suppressive effect on serum prolactin and growth hormone secretion. It is also effective in providing relief from associated effects such as infertility, galactorrhea, oligomenorrhea, amenorrhea, loss of IibMo and impotence. Compared with the most widely used antiprolactin, bromocriptine, quinagolide is more potent in vivo with a longer duration of action and fewer side effects. A recent study showed that acute administration of quinagolide suppresses growth hormone secretion in acromegalic patients and thus could serve as an alternative therapy in acromegaly.

使用

Quinagolide is a nonergot dopamine D2-receptor agonist. Quinagolide acts as an prolactin inhibitor.

キナゴリド 上流と下流の製品情報

原材料

準備製品

キナゴリド 生産企業

Global( 36)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 47465 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
AFINE CHEMICALS LIMITED 		0571-85134551
info@afinechem.com CHINA 15377 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49739 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131981 58
Mainchem Co., Ltd. +86-0592-6210733
sale@mainchem.com China 32360 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited 021-20908456
sales@BioChemBest.com China 6011 61
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2127 70
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15421 60

94424-50-7(キナゴリド)キーワード:

トポテカン塩酸塩 2-エチル-3-ヒドロキシ-4-ピロン N,N-ジイソプロピルエチルアミン エチルセルロース ヒドロキシエチルセルロース 没食子酸プロピル ヒドロキシエチルスターチ エチドロン酸 メフロキン塩酸塩 ジフェニドール塩酸塩 n-酪酸 n-プロピル 3,6-ビス(4-クロロ-2-ホスホノフェニルアゾ)-4,5-ジヒドロキシナフタレン-2,7-ジスルホン酸 キナゴリド (S)-3-アミノピペリジン キノリン 塩酸塩 3-ベンジルピペリジン 1-プロピルピペリジン-3-アミン 4-アミノヒドロけい皮酸
  • 94424-50-7
  • QUINAGOLIDE HYDROCHLORIDE
  • (3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride
  • (3α,4aα,10aβ)-N,N-Diethyl-N'- (1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride
  • Norprolac Hydrochloride
  • rel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride
  • SDZ 205-502
  • Quinagolide hydrochloride (CV205-502 hydrochloride)
  • (+/-)-N,N-diethyl-N'-<(3α,4aα,10aβ)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzoquinolinyl>sulfamide hydrochloride
  • CV205-502 hydrochloride
  • キナゴリド塩酸塩
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