Ponazuril
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Ponazuril 속성
- 녹는점
- 242°
- 밀도
- 1.507±0.06 g/cm3(Predicted)
- 저장 조건
- Refrigerator
- 용해도
- 아세톤트릴 (약간 용해됨), DMSO (약간 용해됨), 메탄올 (약간 용해됨)
- 산도 계수 (pKa)
- 6.46±0.20(Predicted)
- 색상
- 흰색에서 황백색까지
- InChIKey
- VBUNOIXRZNJNAD-UHFFFAOYSA-N
- CAS 데이터베이스
- 69004-04-2
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| WGK 독일 | 3 |
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| 그림문자(GHS): |
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| 신호 어: | Warning | |||||||||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Ponazuril C화학적 특성, 용도, 생산
개요
Toltrazuril sulfone is an active metabolite of the coccidiostat toltrazuril . Toltrazuril sulfone is formed from toltrazuril via the intermediate metabolite toltrazuril sulfoxide by cytochrome P450 (CYP) enzymes, including CYP3A. It inhibits T. gondii tachyzoite production in African green monkey kidney cells when used at concentrations of 0.1, 1, and 5 μg/ml. Toltrazuril sulfone completely prevents infection with T. gondii tachyzoites in a mouse model of fatal toxoplasmosis when administered at doses of 10 or 20 mg/kg one day prior to, and daily for 10 days following, infection. It also reduces the number of infected mice in the same model when administered at a dose of 10 mg/kg for 11 days starting six days following infection. Formulations containing toltrazuril sulfone have been used in the treatment of equine protozoal myeloencephalitis (EPM) in horses.용도
Toltrazuril sulfone is antiprotazoal, used to treat Equine Protozoal Myeloencephalitis (EPM).Veterinary Drugs and Treatments
Ponazuril is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona.Ponazuril could potentially be useful in treating Neospora caninum and Toxoplasma infections in dogs or cats.
Ponazuril 준비 용품 및 원자재
원자재
준비 용품
Ponazuril 공급 업체
글로벌( 139)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Masteam Bio-tech Co., Ltd. | +86-15200345168 +86-15200345168 |
bruce.lei@masteam.com | CHINA | 153 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12453 | 58 |
| Anhui Yiao New Material Technology Co., Ltd | +86-199-55145978 +8619955145978 |
sales8@anhuiyiao.com | China | 253 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +86-13474506593 +86-13474506593 |
sarah@tnjone.com | China | 794 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9352 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Casorganics US Corp | +17326109938 |
sales@casorganics.com | CHINA | 174 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8822 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 |
info@longyupharma.com | China | 2531 | 58 |
Ponazuril 관련 검색:
D-Nebivolol,hydrochloride(1:1)
Nebivolol Impurity 2 HCl (SR,RS)
(+-)-(R*,S*)-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol
Defluoro Nebivolol
(Mixture of DiastereoMers)
Didefluoro Nebivolol
(Mixture of DiastereoMers)
6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran
(-)-Nebivolol
Nebivolol Impurity 28 HCl (SS,RS)
Nebivolol Impurity 3
Nebivolol Impurity 13 HCl (SS,SS)
(2R)-rel-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran
Toltrazuril
4-(Trifluoromethylthio)phenol
1-Methyl-3-{3-methyl-4-[4-(trifluormethylsulfinyl)-phenoxy]-phenyl}-1,3,5-triazin-2,4,6(1H,3H,5H)-trion
1-METHOXY-4-TRIFLUOROMETHANESULFONYL-BENZENE
Ponazuril
1-Methanesulfonyl-4-phenoxy-benzene
1-METHOXY-4-TRIFLUOROMETHYLSULFANYL-BENZENE