유비데카레논

유비데카레논
유비데카레논 구조식 이미지
카스 번호:
303-98-0
한글명:
유비데카레논
동의어(한글):
유비데카레논;유비퀴논10;유비퀴논
상품명:
Coenzyme Q10
동의어(영문):
COENZYME Q10;COQ10;UBIQUINONE;coenzyme Q10 synthetic;UBIQUINONE-10;Conzyme Q10;Q10 COENZYME;Coenzyme Q10 Powder;CoQ10 Ubidecarenone;CoenzymeQ10Ubidecarenone
CBNumber:
CB0121840
분자식:
C59H90O4
포뮬러 무게:
863.34
MOL 파일:
303-98-0.mol
MSDS 파일:
SDS

유비데카레논 속성

녹는점
49-51 °C
끓는 점
715.32°C (rough estimate)
밀도
0.9145 (rough estimate)
굴절률
1.4760 (estimate)
저장 조건
-20°C
용해도
클로로포름에 용해됩니다.
색상
연한 주황색에서 진한 주황색까지
감도
Light Sensitive
Merck
14,9843
BRN
1900141
안정성
안정적이지만 빛이나 열에 민감할 수 있습니다. -20C의 어두운 곳에 보관하십시오. 강한 산화제와 호환되지 않습니다.
InChIKey
ACTIUHUUMQJHFO-DQXDOXBUSA-N
LogP
19.119 (est)
CAS 데이터베이스
303-98-0(CAS DataBase Reference)
EPA
Ubidecarenone (303-98-0)
안전
  • 위험 및 안전 성명
위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 22-24/25-26
WGK 독일 3
RTECS 번호 DK3900000
F 고인화성물질 8-10
TSCA Yes
HS 번호 29146990
독성 LD50 intramuscular in mouse: > 500mg/kg
기존화학 물질 KE-09397
그림문자(GHS):
신호 어:
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
1
0 0

유비데카레논 C화학적 특성, 용도, 생산

화학적 성질

Yellow-Orange Crystalline Powder

출처

Coenzyme Q10 is found in dietary sources. Coenzyme Qmolecules have side chains of differentlengths in different types of organismsbut function in similar ways.

용도

Ubidecarenone is also known as coenzyme Q10 it is a powerful antioxidant that is naturally found in the cells. It acts as a free radical neutraliser.

정의

ChEBI: Coenzyme Q10 is a ubiquinone having a side chain of 10 isoprenoid units. In the naturally occurring isomer, all isoprenyl double bonds are in the E- configuration. It has a role as a human metabolite, a ferroptosis inhibitor and an antioxidant. It is found in animal organs and yeast with active in the citric acid cycle in carbohydrate metabolism.

일반 설명

Ubidecarenone, referred to as coenzyme Q, is abundantly available in human cells, with major proportions being present in vital body organs such as heart and kidneys. It plays an important role in cell metabolism owing to its significant contribution to the electron transport pathway. It is a strong antioxidant and acts as an essential enzyme catalyst in mitochondrial oxidative phosphorylation.

생물학적 활성

Component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Displays neuroprotective activity.

부작용

Mild side effects might include digestive problems such as: Upper abdominal pain; Loss of appetite; Nausea and vomiting; Diarrhea.
Other possible side effects may include: Headaches and dizziness; Insomnia; Fatigue; Skin itching or rashes; Irritability or agitation.

Purification Methods

Purify it by recrystallisation from EtOH, EtOH/Me2CO or Et2O/EtOH and by chromatography on silica gel using isoPrOH/Et2O (3:1) to give orange crystals. It has max 270nm ( 15,170) in pet ether. [Terao et al. J Org Chem 44 868 1979, NMR and MS: Naruta et al. J Org Chem 45 4097 1980, IR: Lester et al. Biochem Biophys Acta 42 1278 1959, NMR: Planta et al. Helv Chim Acta 42 1278 1959; Morton Biochemical Spectroscopy (Adam Hilger, London, 1975) p 491].

유비데카레논 준비 용품 및 원자재

원자재

준비 용품


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