PULCHINENOSIDE B4

PULCHINENOSIDE B4 구조식 이미지
카스 번호:
129741-57-7
상품명:
PULCHINENOSIDE B4
동의어(영문):
Anemoside B4;Pulchinenoside C;Chinensioside A;PULCHINENOSIDE B4;Pulsatilla saponin B4;AnemosideB4 129741-57-7;Anemoside B4 Pulchinenoside B4;Pulchinenoside C (Anemoside B4);Pulchinenoside B4, 98%, from Pulsatilla chinensis (Bunge) Regel;Lup-20(29)-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β,4α)-
CBNumber:
CB01265602
분자식:
C59H96O26
포뮬러 무게:
1221.38
MOL 파일:
129741-57-7.mol

PULCHINENOSIDE B4 속성

녹는점
208-215℃
밀도
1.48
용해도
DMSO : 125 mg/mL (102.34 mM; Need ultrasonic)
물리적 상태
가루
산도 계수 (pKa)
12.50±0.70(Predicted)

안전

PULCHINENOSIDE B4 C화학적 특성, 용도, 생산

개요

Pulchinenoside B4 is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities. It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM. Pulchinenoside B4 (50 and 100 mg/kg twice per day) prevents increases in plasma blood urea nitrogen (BUN) and creatinine levels, markers of kidney injury, in a mouse model of cisplatin-induced nephrotoxicity. It prevents xylene-induced ear edema in mice in a dose-dependent manner. Pulchinenoside B4 (50 mg/kg) inhibits LPS-induced increases in serum TNF-α, IL-6, and IL-1β levels a mouse model of LPS-induced systemic inflammation.

용도

Pulchinenoside C is a triterpenoid saponin extract which acts as a minor molluscicidal agent in addition to tumor necrosis factor-α secretion inhibition. Anti-inflammatory.

PULCHINENOSIDE B4 준비 용품 및 원자재

원자재

준비 용품


PULCHINENOSIDE B4 공급 업체

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