라폰티게닌

라폰티게닌
라폰티게닌 구조식 이미지
카스 번호:
500-65-2
한글명:
라폰티게닌
동의어(한글):
라폰티게닌
상품명:
rhapontigenin
동의어(영문):
Protigenin;rhapontigenin;3-benzenediol;Rhapontigenin >rhapontigenin USP/EP/BP;-5-(3-Hydroxy-4-methoxystyryl);COc2ccc(/C=C/c1cc(O)cc(O)c1)cc2O;(E)-4'-Methoxy-3,3',5-stilbenetriol;3,3',5-Trihydroxy-4'-methoxy-trans-stilbene;5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-1
CBNumber:
CB01309681
분자식:
C15H14O4
포뮬러 무게:
258.27
MOL 파일:
500-65-2.mol
MSDS 파일:
SDS

라폰티게닌 속성

녹는점
189.0 to 193.0 °C
끓는 점
503.6±38.0 °C(Predicted)
밀도
1.345±0.06 g/cm3(Predicted)
저장 조건
4°C, protect from light
용해도
≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
물리적 상태
powder to crystal
산도 계수 (pKa)
9.17±0.10(Predicted)
색상
흰색에서 밝은 노란색
CAS 데이터베이스
500-65-2

안전

HS 번호 2914.50.3000

라폰티게닌 C화학적 특성, 용도, 생산

개요

Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).

용도

Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).[Cayman Chemical]

라폰티게닌 준비 용품 및 원자재

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