chinoin 123
|
|
chinoin 123 속성
- 녹는점
- 154-155 °C(Solv: ethanol (64-17-5))
- 끓는 점
- 472.0±55.0 °C(Predicted)
- 밀도
- 1.39±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 4.45±0.10(Predicted)
안전
chinoin 123 C화학적 특성, 용도, 생산
Originator
Acitemate ,Onbio Inc.Manufacturing Process
23.6 g of 3-ethoxycarbonyl-7-methyl-4-oxo-6,7,8,9-tetrahydro-4Hpyrido[ 1,2a]pyrimidine and 10.0 g of glyoxylic acid monohydrate are reacted and the obtained 3-ethoxycarbonyl-7-methyl-9-carboxy(hydroxymethyl)-4- oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2a]pyrimidine is heated in 150 ml ethanol under stirring for 3 h. After cooling the crystals are filtered off and recrystallized from ethanol. Thus 3-ethoxycarbonyl-7-methyl-9- (carboxymethylene)-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2a]pyrimidine melting point 110°-112°C, is obtained (yield: 51%).55.6 g of 3-ethoxycarbonyl-9-(carboxymethylene)-4-oxo-6,7,8,9-tetrahydro- 4H-pyrido[1,2a]pyrimidine are hydrogenated in 500 ml of ethanol in the presence of 20.0 g of 9% by weight Pd/C catalyst containing metal. When 1 mole of hydrogen has been used up, the catalyst is removed from the reaction mixture by filtration and the solution is evaporated under reduced pressure. The 3-ethoxycarbonyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-9- acetic acid is obtained (yield: 57%), melting point 156°-157°C (recrystallized from ethanol).
Therapeutic Function
Platelet aggregation inhibitor, Antihyperlipidemicchinoin 123 준비 용품 및 원자재
원자재
준비 용품
chinoin 123 공급 업체
글로벌( 2)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24131 | 58 |
chinoin 123 관련 검색:
1-피퍼리딘프로피오니산 에틸(1)피페르딘프로피오네이트
5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-oxo- (9CI)
ETHYL 3-DI-N-PROPYLAMINOPROPIONATE
4-Hydroxypyrimidine-5-carboxylic acid methyl ester
Ethyl 4-hydroxypyrimidine-5-carboxylate
3-ISOPROPYLAMINO-PROPIONIC ACID ETHYL ESTER X HCL >98%
BUTYRAMIDINE
METHYL 3-(PIPERIDIN-1-YL)PROPANOATE
chinoin 123
6-ACRYLAMIDOHEXANOIC ACID
2-DIETHYLAMINOMETHYL-ACRYLIC ACID
ETHYL 3-METHYL-1-PIPERIDINEPROPIONATE, 95
2-PIPERIDIN-1-YLMETHYL-ACRYLIC ACID
3-(3-methylpiperidin-1-yl)propanoic acid
4-HYDROXY-2-METHYLPYRIMIDINE-5-CARBOXYLIC ACID
3-PIPERIDINE ACETIC ACID