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BATRACHOTOXIN

BATRACHOTOXIN 구조식 이미지

카스 번호:: 23509-16-2

상품명:: BATRACHOTOXIN

동의어(영문):: BTX;C13750;BATRACHOTOXIN;ISNYUQWBWALXEY-OMIQOYQYSA-N;Batrachotoxinin A, 20-(2,4-dimethyl-1H-pyrrole-3-carboxylate);1H-Pyrrole-3-carboxylicacid, 2,4-dimethyl-,(1S)-1-[(5aR,7aR,9R,11aS,11bS,12R,13aR)-1,2,3,4,7a,8,9,10,11,11a,12,13-dodecahydro-9,12-dihydroxy-2,11a-dimethyl-7H-9,11b-epoxy-13a,5a-propenophenanthro[2,1-;(1S)-1-[(5aR,7aR,9R,11aS,11bS,12R,13aR)-1,2,3,4,7a,8,9,10,11,11a,12,13-Dodecahydro-9,12-dihydroxy-2-11a-dimethyl-7H-9,11b-epoxy-13a,5a-propenophenanthro[2,1-f][1,4]oxazepin-14-yl]ethyl2,4-dimethyl-1H-pyrrole-3-carboxylate;1H-Pyrrole-3-carboxylic acid, 2,4-dimethyl-, (1S)-1-[(5aR,7aR,9R,11aS,11bS,12R,13aR)-1,2,3,4,7a,8,9,10,11,11a,12,13-dodecahydro-9,12-dihydroxy-2,11a-dimethyl-7H-9,11b-epoxy-13a,5a-propenophenanthro[2,1-f][1,4]oxazepin-14-yl]ethyl ester

CBNumber:: CB01431991

분자식:: C31H42N2O6

포뮬러 무게:: 538.67

MOL 파일:: 23509-16-2.mol

속성

안전

용도

공급 업체 8

BATRACHOTOXIN 속성

알파: 24584 -5 To -10°; 24300 -260° (c = 0.23 in methanol)

끓는 점: 614.87°C (rough estimate)

밀도: 1.1575 (rough estimate)

굴절률: 1.5800 (estimate)

저장 조건: Store at -20°C

산도 계수 (pKa): 7.45(at 25℃)

물리적 상태: 필름같은 재질

색상: 결정체가 아님

CAS 데이터베이스: 23509-16-2

EPA: Betrachotoxinin A, 20-.alpha.-(2,4-dimethyl-1H-pyrrole-3-carboxylate) (23509-16-2)

안전

유엔번호(UN No.)	3172
위험 등급	6.1(b)
포장분류	III
유해 물질 데이터	23509-16-2(Hazardous Substances Data)
독성	LD50 s.c. in mice: 2 mg/kg (Tokuyama)

BATRACHOTOXIN C화학적 특성, 용도, 생산

화학적 성질

Noncrystal.

위험도

Extremely toxic; deadly poison; neurotoxic; cardiotoxic activity; bara-chotoxin that blocks neuromuscular transmission; respiratory paralysis; death.

생물학적 활성

Potent neurotoxin that activates voltage-gated sodium channels. Shifts voltage-dependent activation to more negative potentials, inactivation is disabled and pore conductance and selectivity are altered (displays increased permeability for NH 4 + , K + and Cs + ions).

Safety Profile

A deadly poison byintraperitoneal, intravenous, and subcutaneous routes.When heated to decomposition it emits toxic fumes ofNOx.

효소 저해제

This lipid-soluble neurotoxin (FW = 526.67 g/mol; CAS 23509-16-2; LD50 = ~2 μg/kg mouse body weight.), isolated from the skin of the Columbian poison-dart frog Phyllobates aurotaenis, enhances Na+ conductance, promoting opening of voltage-gated Na+ channels, inducing depolarization of the resting membrane potential. It does so by binding to the sodium channel, keeping the membrane permeable to sodium ions in an all-or-none manner. This results in hyperexcitability of excitable tissues, followed by convulsions, paralysis, and death in animals. The most common use of batrachotoxin is in darts for bloguns used in hunting by the Noanamá Chocó and Emberá Chocó Indians of western Colombia. Batrachotoxin has also been identified in the feathers of the passerine birds of New Guinea Pitohui dichrous, Pitohui kirhocephalus, and Ifrita kowaldi. The less toxic batrachotoxin A is the deesterified steroid.

BATRACHOTOXIN 준비 용품 및 원자재

원자재

준비 용품

BATRACHOTOXIN 공급 업체

글로벌( 8)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58

BATRACHOTOXIN 관련 검색:

베타-테르핀올 Tetracaine hydrochloride Aconitine VERATRIDINE TETRODOTOXIN QX-314 L-KAWAIN PD 85639 (+)-ISOPULEGOL DIHYDROCARVEOL (-)-DIHYDROCARVEOL 2,5-DIMETHYL-1,5-HEXADIEN-3-OL BATRACHOTOXIN CIS-2-AMINOMETHYL-1-METHYL-CYCLOHEXANOL 1-ALLYL-1-METHOXY-CYCLOHEXANE homobatrachotoxin (E)-4-ETHOXY-NONA-1,5-DIENE 2-METHOXY-2-METHYL-BUT-3-EN-1-OL