TIN PROTOPORPHYRIN IX DICHLORIDE
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TIN PROTOPORPHYRIN IX DICHLORIDE 속성
- 저장 조건
- Store at RT
- 용해도
- Soluble to 25 mM in 1eq. NaOH and to 5 mM in DMSO
- 물리적 상태
- 진한 빨간색에서 보라색 고체.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
TIN PROTOPORPHYRIN IX DICHLORIDE C화학적 특성, 용도, 생산
용도
Heme oxygenase (HO) converts protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin . While HO-2 is constitutively expressed, HO-1 can be induced by its heme substrate as well as by heavy metals, oxidizing agents, and other environmental stresses. TIN PROTOPORPHYRIN IX DICHLORIDE(SnPPIX) is a synthetic heme analog that selectively inhibits HO-1 (Ki = 11 nM) over HO-2 (IC50 = 7.5 μM). It also weakly inhibits endothelial nitric oxide synthase and soluble guanylyl cyclase (IC50s = 35 and 30 nM, respectively). SnPPIX prevents hyperbilirubinemia in neonates by blocking HO-1 activity that increases postnatally. It is rapidly cleared from plasma and persists in certain tissues, including kidney, liver, and spleen. SnPPIX is commonly used as a tool to study the role of HO-1 activity in cells and in animals.[Cayman Chemical]TIN PROTOPORPHYRIN IX DICHLORIDE 준비 용품 및 원자재
원자재
준비 용품
TIN PROTOPORPHYRIN IX DICHLORIDE 공급 업체
글로벌( 43)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 |
CHINA | 964 | 58 | |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33349 | 58 |
Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 |
sales-cpd@caerulumpharma.com | China | 3419 | 58 |
Chengdu Aslee Biopharmaceuticals, Inc | 028-85305008 02885305008 |
2306208234@qq.com | China | 1004 | 50 |