GLP-1
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GLP-1 속성
- 저장 조건
- −20°C
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 수용성
- Soluble to 5 mg/ml in water
- InChIKey
- UKVFVQPAANCXIL-FJVFSOETSA-N
- CAS 데이터베이스
- 87805-34-3
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 | ||
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HS 번호 | 3504009000 |
그림문자(GHS): | |||||||||||||||||||||||||||||
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신호 어: | Warning | ||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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GLP-1 C화학적 특성, 용도, 생산
역사
GLP-1 was first identified in the early 1980s, following the cloning of the proglucagon gene. The biological activity of GLP-1 was investigated initially by using the N-terminal extended forms of GLP-1(1–37 and 1–36 amide). However, these forms were devoid of biological activity. In the late 1980s, bioactive GLP-1 peptides were purified from gut extracts and were identified to be GLP1(7–37) and GLP-1(7–36)-amide. In the current literature, the unqualified designation of GLP-1 corresponds to the truncated peptides.용도
Glucagon-Like Peptide I (GLP1) has been used as an antigen in excess amounts for the incubation of primary antibodies, post-immunocytochemistry with positive results of paraffin-embedded pancreatic tissues of Rana temporaria.일반 설명
Glucagon-Like Peptide I (GLP1) is an incretin hormone, which functions as ligand for GLP1 receptors (GLP1R). These receptors are expressed in renal and cardiovascular system, such as smooth muscle and endothelial cells.Biochem/physiol Actions
Glucagon-Like Peptide I (GLP1) controls the metabolism of glucose, by inducing the secretion of insulin and suppressing that of glucagon. Studies in Indonesian population show that reduced levels of this protein are linked with increased susceptibility to type 2 diabetes mellitus. Plasma levels of this hormone also show significant association with systolic and diastolic blood pressure levels.부작용
Common side effects of GLP-1 include: loss of appetite, nausea, vomiting, diarrhoea. Other side effects may include: dizziness, mild tachycardia or increased heart rate, infection, headache, and indigestion. Temporary mild itching and redness of the skin at the injection site may also occur. Serious and rare side effects include: pancreatitis, medullary thyroid cancer, acute (sudden) kidney injury, worsening of diabetes-related retinopathy, and severe allergic reactions. And GLP-1 agonists are recommended during pregnancy because they can cause abnormal foetal development. Seek medical attention if any serious adverse reactions occur.GLP-1 준비 용품 및 원자재
원자재
준비 용품
GLP-1 공급 업체
글로벌( 125)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
Strong peptide cross-border e-commerce Co. LTD | +undefined13930052870 |
qt01@qiangtaipharm.com | China | 84 | 58 |
Qingdao Xinli Technology Development Co., Ltd. | +8616632313095 |
xinlikeji01@qdxlchem.com | China | 134 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 973 | 58 |
Shanghai Affida new material science and technology center | +undefined15081010295 |
admin@oudaxin.com | China | 114 | 58 |
Sigma Audley | +86-15937194204 +86-18126314766 |
nova@sh-teruiop.com | China | 491 | 58 |
Hebei Kangcang new material Technology Co., LTD | +8615713292910 |
Nancy@kangcang.com.cn | China | 341 | 58 |
CONTIDE BIOTECH CO.,LTD | +44-7438349267 +44-7438349267 |
xena@healthtide-api.com | China | 562 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
GLP-1 관련 검색:
아세틸아세톤산 구리 코발트(II) 아세틸아세토네이트 하이드레이트 아세틸아세토산 제2철 알루미늄 아세틸아세토네이트 실버 아세틸아세토네이트 디스프로슘 트리(2,2,6,6-테트라메틸-3,5-헵탄디오네이트)
L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-2-methylalanyl-L-alanyl-L-arginyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-α-glutamy...
glucagon-like peptide 1
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GLUCAGON-37 (HUMAN, MOUSE, RAT)
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