LUFFARIELLOLIDE
|
|
LUFFARIELLOLIDE 속성
- 끓는 점
- 541.7±50.0 °C(Predicted)
- 밀도
- 1.006±0.06 g/cm3(Predicted)
- 용해도
- DMSO: soluble; Ethanol: soluble
- 산도 계수 (pKa)
- 9.98±0.40(Predicted)
- 물리적 상태
- 연한 노란색 오일.
- InChI
- InChI=1S/C25H38O3/c1-18(11-7-13-21-17-23(26)28-24(21)27)9-6-10-19(2)14-15-22-20(3)12-8-16-25(22,4)5/h10-11,17,24,27H,6-9,12-16H2,1-5H3/b18-11+,19-10+
- InChIKey
- JPWPYTMXSXYUPG-QZPYEDBESA-N
- SMILES
- O1C(O)C(CC/C=C(\C)/CC/C=C(\C)/CCC2C(C)(C)CCCC=2C)=CC1=O
안전
LUFFARIELLOLIDE C화학적 특성, 용도, 생산
용도
Luffariellolide is a natural sesterterpenoid which reversibly inhibits secretory phospholipase A2 isoforms from bee venom (IC50 = 230 nM) and snake venom, reducing inflammation. It blocks the production of platelet-activating factor in stimulated neutrophils (IC50 = 5 μM). Luffariellolide is also a structural mimic of all-trans retinoic acid (RA) and, at 1 μM, acts as an agonist for the RA receptors RAR α, β, and γ but not for other nuclear receptors. In RA-sensitive cancer cell lines, luffariellolide induces the expression of RAR target genes and inhibits cell growth. It also inhibits the activation of hypoxia-inducible factor by hypoxia (IC50 = 3.6 μM).[Cayman Chemical]LUFFARIELLOLIDE 준비 용품 및 원자재
원자재
준비 용품
LUFFARIELLOLIDE 공급 업체
글로벌( 37)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44894 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
QUALITY CONTROL SOLUTIONS LTD. | 0755-66853366 15920483169 |
sales@chem-strong.com | China | 18810 | 58 |
amyjetsci | 027-59626688 18771149750 |
sales@amyjet.com | China | 3004 | 58 |
Wuhan Augda Biotechnology Co., Ltd | 15071299552 |
262933239@qq.com | China | 6637 | 58 |
Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 |
czbjpharma@126.com | China | 18488 | 58 |