MYRIOCIN
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MYRIOCIN 속성
- 녹는점
- 170-172℃
- 끓는 점
- 636.7±55.0 °C(Predicted)
- 밀도
- 1.123±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- 메탄올: 2mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 1.79±0.50(Predicted)
- 색상
- 회백색
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 -20°에서 최대 4개월 동안 보관할 수 있습니다.
- InChIKey
- ZZIKIHCNFWXKDY-XFXZXTDPSA-N
- CAS 데이터베이스
- 35891-70-4
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22 | ||
| 안전지침서 | 24/25 | ||
| 유엔번호(UN No.) | UN 2811 6.1/PG 3 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | JX3890000 | ||
| HS 번호 | 29225090 |
MYRIOCIN C화학적 특성, 용도, 생산
개요
Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10-화학적 성질
White powder용도
Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine palmitoyltransferase and thus blocks the synthesis ceramide, a precursor in sphingomyelin and glycosphingolipid biosynthesis. As a result Myriocin i s a useful biochemical research tool for depleting cells of sphingolipids.정의
ChEBI: An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.일반 설명
A potent immunosuppressant. Displays 10- to 100-fold more potent immunosuppressant activity than cyclosporin A. Potently inhibits serine palmitoyltransferase (SPT; Ki = 280 pM) thereby blocking the synthesis of ceramide. Disrupts substratum adhesion of melanoma cells. Inhibits cell proliferation and induces apoptosis in IL-2 dependent murine cytotoxic T lymphocyte cell line CTLL-2.MYRIOCIN 준비 용품 및 원자재
원자재
준비 용품
MYRIOCIN 공급 업체
글로벌( 130)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 |
shchemsky@sina.com | China | 15421 | 60 |
| Syntechem Co.,Ltd | |
info@syntechem.com | China | 12990 | 57 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18521732826; |
market@aladdin-e.com | China | 25015 | 65 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 |
tauto@tautobiotech.com | China | 3989 | 66 |
MYRIOCIN 관련 검색:
메트론이드아졸
Ampicillin
COLISTIN
Ceramides
METYRAPONE
JZL 184
Polymyxin B
Chaetomium globosum
L(+)-allo-Threonine
2-Methyl-D-serine
MYRIOCIN
2-Methyl-L-serine
2-AMINO-3-HYDROXY-2-METHYLBUTANOIC ACID
dl-3-hydroxynorvaline
METHYL 6-TRANS-OCTADECENOATE
(2S,3S)-2-AMINO-3-HYDROXY-PENTANOIC ACID
(2S,3S)-3-HYDROXY-L-ISOVALINE
(D,L)-2-AMINO-HEPT-6-ENOIC ACID