enniatin A

enniatin A 구조식 이미지
카스 번호:
2503-13-1
상품명:
enniatin A
동의어(영문):
enniatin A;Lateritin I;N-Methylcyclo(L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-);(3S,6R,9S,12R,15S,18R)-3,9,15-tris[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)- 2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl- N-methyl-L- isoleucyl]
CBNumber:
CB02079105
분자식:
C36H63N3O9
포뮬러 무게:
681.906
MOL 파일:
2503-13-1.mol

enniatin A 속성

녹는점
122-124 °C
끓는 점
847.4±65.0 °C(Predicted)
밀도
1.022±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMSO: 용해성10mg/mL
물리적 상태
백색 내지 황백색의 결정성 고체.
산도 계수 (pKa)
-0.96±0.70(Predicted)

안전

위험품 표기 T
위험 카페고리 넘버 23/24/25
안전지침서 45
유엔번호(UN No.) 2811
WGK 독일 3
위험 등급 6.1(a)
포장분류 I
HS 번호 2934999090

enniatin A C화학적 특성, 용도, 생산

개요

Enniatins are cyclohexadepsipeptides commonly isolated from fungi that are known to have antibiotic properties and to induce apoptosis in several cancer lines. Many function as ionophores, forming pores in cellular membranes to allow selective ion transport. Enniatin A is one of four major analogs in the enniatin complex . It has been shown to moderately inhibit acyl-CoA:cholesterol acyltranferase activity in rat liver microsomes with an IC50 value of 22 μM. Enniatin A also demonstrates anthelmintic properties against N. brasiliensis, T. spiralis, and H. spumosa.

용도

Enniatins are a family of depsipeptide ionophores, produced by several Fusarium species. More recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumour action have received more focus. Enniatin A is one of four major analogues of the enniatin complex and has not previously been available for investigation.

정의

ChEBI: An enniatin obtained from formal cyclocondensation of three N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-isoleucine units.

enniatin A 준비 용품 및 원자재

원자재

준비 용품


enniatin A 공급 업체

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