WS 12
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WS 12 속성
- 끓는 점
- 447.8±28.0 °C(Predicted)
- 밀도
- 1.029±0.06 g/cm3(Predicted)
- 증기압
- 0-0Pa at 20-50℃
- 저장 조건
- -20°C
- 용해도
- DMSO: >20mg/mL
- 산도 계수 (pKa)
- 14.18±0.70(Predicted)
- 물리적 상태
- 백색 내지 회백색 분말.
- 색상
- 흰색에서 황백색까지
- 냄새
- 100.00%에서. 시원한 민트
- ?? ??
- 민트 맛
- JECFA Number
- 2079
- InChIKey
- HNSGVPAAXJJOPQ-XOKHGSTOSA-N
- LogP
- 3.95 at 22℃ and pH7.7
- CAS 데이터베이스
- 68489-09-8
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WS 12 C화학적 특성, 용도, 생산
개요
WS-12 is an agonist of transient receptor potential melastatin 8 (TRPM8). It induces currents in Xenopus oocytes expressing mouse TRPM8 (EC50 = 12 μM) and is selective for TRPM8 over transient receptor potential vanilloid 1-4 (TRPV1-4) and transient receptor potential ankyrin 1 (TRPA1) at 1 mM. WS-12 (6 nmol, i.c.v.) reduces nocifensive behavior induced by capsaicin in wild-type, but not Trpm8-/-, mice. It induces analgesia in the hot plate test, an effect that can be reversed by the opioid receptor antagonist naloxone, in mice.화학적 성질
WS 12 is a odorless white crystalline solid,mp 178 °C, displaying a strong initial cooling effect and a long-lastingness. It is used particularly is oral care flavors.용도
WS 12 is a potent TRPM8 agonist.상품명
Winsense WS-12 (Renessenz)생물학적 활성
Potent TRPM8 agonist that acts as a cooling agent (EC 50 = 193 nM).WS 12 준비 용품 및 원자재
원자재
준비 용품
WS 12 공급 업체
글로벌( 105)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 |
sales@zhswyy.com | China | 338 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 |
marketing1@neostarunited.com | China | 8349 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| Zhuoer Chemical Co., Ltd | 02120970332; +8613524231522 |
sales@zhuoerchem.com | China | 3015 | 58 |
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 |
mack@tongyon.com | China | 2996 | 58 |