Foretinib (GSK1363089)
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Foretinib (GSK1363089) 속성
- 녹는점
- >98°C (dec.)
- 끓는 점
- 828.5±65.0 °C(Predicted)
- 밀도
- 1.372
- 저장 조건
- Sealed in dry,Store in freezer, under -20°C
- 용해도
- DMSO(약간 용해됨), 에탄올(약간 용해됨)
- 산도 계수 (pKa)
- 13.14±0.70(Predicted)
- 물리적 상태
- 노란색 가루.
- 색상
- 연한 노란색에서 노란색까지
- CAS 데이터베이스
- 849217-64-7
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Foretinib (GSK1363089) C화학적 특성, 용도, 생산
개요
Foretinib is a multikinase inhibitor that targets MET and VEGFR2 and also exhibits an inhibitory effect against KIT, Flt-3, PDGFRb, and Tie-2.용도
Foretinib (GSK1363089) is an ATP-competitive inhibitor of hepatocyte growth factor (HGF) and Vascular endothelial growth factor (VEGF) Receptor Tyrosine Kinases.Clinical Use
Foretinib has also shown to be effective against ROS1 mutations especially when acquired with crizotinib resistance. A clinical trial investigating the dosing and safety profile of combining foretinib and erlotinib was designed for advanced pretreated NSCLC patients.Foretinib (GSK1363089) 준비 용품 및 원자재
원자재
준비 용품
Foretinib (GSK1363089) 공급 업체
글로벌( 175)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 |
chloewu@chicopharm.cn | CHINA | 341 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 |
info@pbpharm.com | CHINA | 498 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |