피페라진 디하이드로클로라이드

피페라진 디하이드로클로라이드 속성

피페라진 디하이드로클로라이드 C화학적 특성, 용도, 생산

용도

Piperazine Dihydrochloride is an anthelmintic agent used in the treatment of parasitic worms in animals.

일반 설명

White to cream-colored needles or powder. Mp: 318-20°C (with decomposition).

반응 프로필

PIPERAZINE DIHYDROCHLORIDE is incompatible with the following: Water, HEAT, flames, oxidizers. PIPERAZINE DIHYDROCHLORIDE absorbs moisture from air. PIPERAZINE DIHYDROCHLORIDE may create flammable condition upon contact with HEAT, FLAMES and OXIDIZERS.

Safety Profile

Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used in making fiber, pharmaceuticals, and insecticides. See also PIPERAZINE.

잠재적 노출

Agricultural chemical, Suspected reprotoxic hazard. Piperazine is used to manufacture anthelmintics, antifilarials, antihistamines, and tranquilizers; the dihydrochloride is used in the manufacture of fibers, pharmaceuticals and insecticides. They are used as an intermediate in the manufacture of, pesticides, rubber chemicals and fibers. Also, piperazine is widely available, effective, and safe when used on an occasional basis against ascaride infections. It is also considerably cheaper than other anthelminthic drugs. In some countries where ascariasis is not endemic and where piperazine was used predominantly for the treatment of pinworn, it has been withdrawn from use on the grounds that other effective drugs are now available. Clinical dosages occasionally induce transient neurological signs and, in some circumstances, the drug may generate small amounts of nitrosamine in the stomach, which at considerably greater dosage in experimental animals has been demonstrated to have a carcinogenic potential.

Carcinogenicity

Piperazine dihydrochloride is an irritant and sensitizer. Little information exists on the toxicology of piperazine dihydrochloride in humans or in animals. Acute human exposures to the dust have reportedly resulted in irritation to the eyes, mild to moderate skin burns, and sensitization. Exposure levels and duration were not available.

Purification Methods

Crystallise the salt from aqueous EtOH and dry it at 110o. [Beilstein 23 III/IV 17, 23/1 V 30.]

비 호환성

Aqueous solution is a strong base. Violent reaction with strong oxidizers and dicyanofurazan. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, nitrogen compounds, carbon tetrachloride. Attacks aluminum, copper, nickel, magnesium and zinc.

피페라진 디하이드로클로라이드 준비 용품 및 원자재

원자재

준비 용품

피페라진 디하이드로클로라이드 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Nanjing Deda New Material Technology Ltd.	+8613223281135	niki@njdeda.com	China	76	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	16803	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28965	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Alfa Chemistry		info@alfa-chemistry.com	United States	2344	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58

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