SCIADOPITYSIN

SCIADOPITYSIN 구조식 이미지
카스 번호:
521-34-6
상품명:
SCIADOPITYSIN
동의어(영문):
Nsc 45108;SCIADOPITYSIN;Einecs 208-311-5;SCIADOPITYSIN(SH);4',4''',7-Trimethoxyamentoflavone;AMENTOFLAVONE-7,4',4'-TRIMETHYL ETHER;AMENTOFLAVONE-7,4',4''-TRIMETHYL ETHER;AMENTOFLAVONE-7,4',4'''-TRIMETHYL ETHER;Sciadopitysin, 95%, from Ginkgo biloba L.;AMENTOFLAVONE-7,4'',4''-TRIMETHYL ETHER WITH HPLC
CBNumber:
CB0273404
분자식:
C33H24O10
포뮬러 무게:
580.54
MOL 파일:
521-34-6.mol
MSDS 파일:
SDS

SCIADOPITYSIN 속성

녹는점
296-298°C
끓는 점
839.6±65.0 °C(Predicted)
밀도
1.445±0.06 g/cm3(Predicted)
저장 조건
2-8°C
용해도
Soluble in ethanol and methan
물리적 상태
가루
산도 계수 (pKa)
6.16±0.40(Predicted)
색상
연노랑
LogP
5.500 (est)
CAS 데이터베이스
521-34-6

안전

안전지침서 24/25
HS 번호 29329990

SCIADOPITYSIN C화학적 특성, 용도, 생산

개요

Sciadopitysin is a biflavonoid originally isolated from G. biloba and has diverse biological activities. It reduces cytotoxicity induced by amyloid-β (1-42) (Aβ42; ) in PC12 cells (EC50 = 9.84 μM). Sciadopitysin (0.1-10 μM) decreases methylglyoxal-induced insulin secretion, production of reactive oxygen species (ROS), cardiolipin peroxidation, and cytotoxicity in RIN-m5F pancreatic β-cells. It inhibits P-glycoprotein (P-gp; IC50 = 53.42 μM) and increases cellular toxicity of paraquat and paclitaxel in MDR1-MDCKII cells. Sciadopitysin inhibits RANKL-induced mRNA expression of the osteoclast-specific genes CTSK, TRAP, and MMP-9, activation of NF-κB, and osteoclastogenesis in a mouse model of LPS-induced bone loss.

정의

ChEBI: A biflavonoid that is a 7, 4', 4'''-trimethyl ether derivative of amentoflavone.

SCIADOPITYSIN 준비 용품 및 원자재

원자재

준비 용품


SCIADOPITYSIN 공급 업체

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Chengdu GLP biotechnology Co Ltd
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Chengdu Biopurify Phytochemicals Ltd.
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Hubei Jusheng Technology Co.,Ltd.
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BOC Sciences
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Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386
marketing1@neostarunited.com China 8349 58

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