N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride

N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride C화학적 특성, 용도, 생산

Biochem/physiol Actions

CP-338818 blocks both Kv1.3 and Kv1.4. Kv1.3 is expressed in brain and in effector memory T (Tem) cells, and Kv1.4 is expressed in brain cells. Kv1.3 and Kv1.4 are members of the Shaker family of voltage-gated potassium channels. Both channels are involved in setting the membrane potential of neurons. In addition, Kv1.3 maintains the membrane potential for T memory cells and is up-regulated upon T cell activation, contributing to multiple immune processes and disorders. Blockers of Kv1.3 have long been sought for therapeutic benefit, and they are also valuable tools for studying the immune system. CP-339818 is valuable for immune system studies, where the absence of Kv1.4 makes it functionally selective for Kv1.3, and it has shown suppression of T cell activation. CP-339818 is also valuable for the study of Kv1.4 function.

N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride 준비 용품 및 원자재

원자재

준비 용품

N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride 공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
BOC Sciences	--	info@bocsci.com	USA	0	65
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Wuhan Augda Biotechnology Co., Ltd	15071299552	262933239@qq.com	China	6637	58
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	61720	58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.	+86-027-59232304 15387063101	2881924050@qq.com	China	9991	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58