Tiamulin fumarate
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Tiamulin fumarate 속성
- 녹는점
- 147-148°C
- 끓는 점
- 563℃
- 인화점
- >110°(230°F)
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름(약간 용해됨), 에탄올(약간 용해됨), 메탄올(약간 용해됨)
- 색상
- 하얀색
- 수용성
- 물에 용해됨
- Merck
- 13,9495
- InChIKey
- YXQXDXAHCSEVSD-IHAONTCTSA-N
- SMILES
- C(/C(=O)O)=C\C(=O)O.C[C@H]1[C@@H]([C@](C[C@@H](OC(=O)CSCCN(CC)CC)C2([C@H](C)CCC31CCC(=O)[C@]32[H])C)(C)C=C)O |&1:9,10,11,13,27,36,r|
- CAS 데이터베이스
- 55297-96-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22 | ||
| 안전지침서 | 36 | ||
| 유엔번호(UN No.) | UN2811 6.1/PG 3 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | AG9560000 | ||
| HS 번호 | 29419090 | ||
| 기존화학 물질 | KE-10404 |
Tiamulin fumarate C화학적 특성, 용도, 생산
화학적 성질
White Solid. soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide.용도
Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis. It is a derivative of Pleuromutilin with Antibacterial that targets Gram-positive bacteria as well as a few mycoplasma species.주요 응용
Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity. The hemi-fumarate provides a stable salt with improved water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action of inhibiting protein synthesis by binding to domain V of 23S rRNA.Indications
Tiamulin fumarate is mainly used for Mycoplasma suis pneumonia, Haemophilus parasuis, infectious pleuropneumonia and dysentery caused by Treponema swine, and also for chronic respiratory tract of poultry, Mycoplasma pneumonia, infectious rhinitis, Escherichia coli, duck Infectious serositis.건강위험
Inhalation may irritate (cough, short breathing, difficulty in breathing). Headache. It may cause moderate irritation, including a burning sensation, tearing, redness, or swelling. Itching. Causes serious eye irritation. Redness, itching, tears. Stinging. It may cause irritation to the digestive tract. Abdominal pain, nausea.Mode of action
Tiamulin fumarate is a bacteriostatic antibiotic belonging to the pleuromutilin class, which inhibit protein synthesis by targeting the 50S bacterial ribosomal subunit and binding to peptidyl transferase, the enzyme responsible for forming peptide bonds between amino acids.Tiamulin fumarate 준비 용품 및 원자재
원자재
준비 용품
Tiamulin fumarate 공급 업체
글로벌( 378)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Masteam Bio-tech Co., Ltd. | +86-15200345168 +86-15200345168 |
bruce.lei@masteam.com | CHINA | 153 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 |
sales@sdperfect.com | China | 294 | 58 |
| Henan Suikang Pharmaceutical Co.,Ltd. | +8618239973690 |
sales@suikangpharm.com | China | 178 | 58 |
| Hebei Dangtong Import and export Co LTD | +8615632927689 |
admin@hbdangtong.com | China | 991 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 893 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 2259 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |